DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11456 and Plagl2

DIOPT Version :9

Sequence 1:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_061277.2	Gene:	Plagl2 / 54711	MGIID:	1933165	Length:	496	Species:	Mus musculus

Alignment Length:	158	Identity:	51/158 - (32%)
Similarity:	74/158 - (46%)	Gaps:	14/158 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 PSSKKNKYYAEKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNV--CGKKTARKASLIIHMRQH 281
            |..::.:...:..|||....|.||:.|..| ...|.:.:|:.|..  |||..|.|..|..||..|
Mouse    29 PRGREAESQVKCQCEISGTPFSNGEKLRPH-SLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATH 92

  Fly   282 TGEKPLQCGEC--KFSTRDPSVLHKHRQRHDSQDTRSSLKCSQCDYFCIQANALKRHMRLNHAEA 344
            :.:||.||..|  .|..:|.  |..|.|.||  ..:.:|.||:|..........:||:.: ||.:
Mouse    93 SAQKPHQCMYCDKMFHRKDH--LRNHLQTHD--PNKEALHCSECGKNYNTKLGYRRHLAM-HAAS 152

  Fly   345 YRDLCCDIC--SFTSIN--VERLRAHKQ 368
            ..||.|.:|  :|.|..  :|.|:||.:
Mouse   153 SGDLSCKVCLQTFESTQALLEHLKAHSR 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	8/20 (40%)
		C2H2 Zn finger	261..281	CDD:275368	9/21 (43%)
		C2H2 Zn finger	289..309	CDD:275368	7/21 (33%)
Plagl2	NP_061277.2	C2H2 Zn finger	42..62	CDD:275368	8/20 (40%)
		C2H2 Zn finger	70..92	CDD:275368	9/21 (43%)
		zf-H2C2_2	85..109	CDD:372612	10/23 (43%)
		C2H2 Zn finger	100..120	CDD:275368	7/21 (33%)
		C2H2 Zn finger	129..149	CDD:275368	5/20 (25%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	193..213	CDD:275368
		C2H2 Zn finger	221..239	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100