DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11456 and Zfp316

DIOPT Version :9

Sequence 1:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_059495.3	Gene:	Zfp316 / 54201	MGIID:	1860402	Length:	1017	Species:	Mus musculus

Alignment Length:	264	Identity:	74/264 - (28%)
Similarity:	106/264 - (40%)	Gaps:	62/264 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 EKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCGEC- 292
            |.||::|.:.|.:...|:|| :..|..:|||.|:.|||....::.|.||.|.||||||..|.:|
Mouse   340 ETTCDVCGKVFPHRSRLAKH-QRYHAAVKPFGCDECGKGFVYRSHLAIHQRTHTGEKPFPCPDCG 403

  Fly   293 -KFSTRDPSVLHK--------------------------HRQRHDSQDTRSSLKCSQCDYFCIQA 330
             :|..:...|.|:                          |::.|..:   ....|..|.....|:
Mouse   404 KRFVYKSHLVTHRRIHTGERPYRCVFCGAGFGRRSYLVTHQRTHTGE---RPYPCLHCGRSFSQS 465

  Fly   331 NALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQ-GLITNCEDSMDARAAGFKYPRK 394
            :||.||..::.|:  |..||..|.    ...||||..|.||: |..|.......||.|    |.:
Mouse   466 SALARHQAVHTAD--RPHCCPDCG----QAFRLRADFQRHRRSGGCTEPSSGDGARMA----PHE 520

  Fly   395 VGDKNGE----ISADCFMPLESVDSLPHEPALDTGGV--------------TIPAPPSEDTQFPT 441
            ||....|    ::|...:..|.:::.|.|......||              .:.||.:|.| .|.
Mouse   521 VGMAPNEVEMAVAAVATVEPEELEAAPAETEEPEAGVADGDTEAEARQDEQVVVAPAAEAT-VPD 584

  Fly   442 YLKD 445
            ..||
Mouse   585 SKKD 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	6/20 (30%)
		C2H2 Zn finger	261..281	CDD:275368	8/19 (42%)
		C2H2 Zn finger	289..309	CDD:275368	6/47 (13%)
Zfp316	NP_059495.3	KRAB	155..215	CDD:214630
		COG5048	<339..499	CDD:227381	50/168 (30%)
		C2H2 Zn finger	343..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..391	CDD:275368	8/19 (42%)
		zf-H2C2_2	383..408	CDD:372612	13/24 (54%)
		C2H2 Zn finger	399..419	CDD:275368	5/19 (26%)
		C2H2 Zn finger	427..447	CDD:275368	1/19 (5%)
		C2H2 Zn finger	455..475	CDD:275368	7/19 (37%)
		C2H2 Zn finger	483..501	CDD:275368	8/21 (38%)
		PRK13108	<507..584	CDD:237284	17/81 (21%)
		C2H2 Zn finger	710..730	CDD:275368
		zf-C2H2	710..730	CDD:333835
		zf-H2C2_2	722..747	CDD:372612
		C2H2 Zn finger	738..758	CDD:275368
		COG5048	<763..950	CDD:227381
		C2H2 Zn finger	766..786	CDD:275368
		C2H2 Zn finger	794..814	CDD:275368
		C2H2 Zn finger	822..842	CDD:275368
		C2H2 Zn finger	850..870	CDD:275368
		C2H2 Zn finger	878..898	CDD:275368
		C2H2 Zn finger	906..926	CDD:275368
		C2H2 Zn finger	934..954	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100