DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11456 and Zfp316

DIOPT Version :9

Sequence 1:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001100591.1	Gene:	Zfp316 / 304293	RGDID:	1311647	Length:	1016	Species:	Rattus norvegicus

Alignment Length:	226	Identity:	65/226 - (28%)
Similarity:	95/226 - (42%)	Gaps:	48/226 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 EKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCGEC- 292
            |.||::|.:.|.:...|:|| :..|..:|||.|..|||....::.|.||.|.||||||..|.:|
  Rat   336 ETTCDVCGKVFPHRSRLAKH-QRYHAAVKPFGCEECGKGFVYRSHLAIHQRTHTGEKPFPCPDCG 399

  Fly   293 -KFSTRDPSVLHK--------------------------HRQRHDSQDTRSSLKCSQCDYFCIQA 330
             :|..:...|.|:                          |::.|..:   ....|..|.....|:
  Rat   400 KRFVYKSHLVTHRRIHTGERPYRCVFCGAGFGRRSYLVTHQRTHTGE---RPYPCLHCGRSFSQS 461

  Fly   331 NALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQGLITNCEDSMDARAAGFKYPRKV 395
            :||.||..::.|:  |..||..|.    ...||||..|.||:|  ..|.:......| ...|.:|
  Rat   462 SALARHQAVHTAD--RPHCCPDCG----QAFRLRADFQRHRRG--GGCTEPSSGDGA-LTAPHEV 517

  Fly   396 GDKNGEISADCFMPLESVDSL-PHEPALDTG 425
            |....|:.    |.:.:|.:. |.|  |::|
  Rat   518 GMAPNEVE----MAIAAVATAEPEE--LESG 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	6/20 (30%)
		C2H2 Zn finger	261..281	CDD:275368	8/19 (42%)
		C2H2 Zn finger	289..309	CDD:275368	6/47 (13%)
Zfp316	NP_001100591.1	KRAB	151..211	CDD:214630
		KRAB	151..190	CDD:279668
		COG5048	<335..495	CDD:227381	50/168 (30%)
		C2H2 Zn finger	339..359	CDD:275368	6/20 (30%)
		C2H2 Zn finger	367..387	CDD:275368	8/19 (42%)
		zf-C2H2	367..387	CDD:278523	8/19 (42%)
		zf-H2C2_2	379..404	CDD:290200	13/24 (54%)
		C2H2 Zn finger	395..415	CDD:275368	5/19 (26%)
		zf-H2C2_2	407..432	CDD:290200	2/24 (8%)
		C2H2 Zn finger	423..443	CDD:275368	1/19 (5%)
		zf-H2C2_2	435..460	CDD:290200	4/27 (15%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		zf-H2C2_2	463..486	CDD:290200	9/28 (32%)
		C2H2 Zn finger	479..497	CDD:275368	8/21 (38%)
		C2H2 Zn finger	707..727	CDD:275368
		zf-H2C2_2	719..744	CDD:290200
		C2H2 Zn finger	735..755	CDD:275368
		zf-H2C2_2	747..772	CDD:290200
		COG5048	<760..947	CDD:227381
		C2H2 Zn finger	763..783	CDD:275368
		zf-H2C2_2	775..800	CDD:290200
		C2H2 Zn finger	791..811	CDD:275368
		C2H2 Zn finger	819..839	CDD:275368
		zf-C2H2	845..867	CDD:278523
		C2H2 Zn finger	847..867	CDD:275368
		zf-H2C2_2	859..884	CDD:290200
		C2H2 Zn finger	875..895	CDD:275368
		zf-H2C2_2	887..912	CDD:290200
		C2H2 Zn finger	903..923	CDD:275368
		zf-H2C2_2	916..940	CDD:290200
		C2H2 Zn finger	931..951	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100