DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11456 and ZNF787

DIOPT Version :9

Sequence 1:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001002836.2	Gene:	ZNF787 / 126208	HGNCID:	26998	Length:	382	Species:	Homo sapiens

Alignment Length:	299	Identity:	68/299 - (22%)
Similarity:	101/299 - (33%)	Gaps:	99/299 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 NYKSPISALVWRHMQVHKKWRPRVLRSLAAVQRRRKLKEQSAEMAAQPAALPPSSKKNKYYAEKT 231
            ::::|:..|:.....| ..|.|..|               |...:|.||..||..:....|   .
Human    22 SHENPVDILIMDDDDV-PSWPPTKL---------------SPPQSAPPAGPPPRPRPPAPY---I 67

  Fly   232 CEICNRKFVNGKTLSKHVKT---------------------------VHNKIKPFICNVCGKKTA 269
            |..|.:.|.:...|::|.:|                           :|...||:.|..|||:.:
Human    68 CNECGKSFSHWSKLTRHQRTHTGERPNACADCGKTFSQSSHLVQHRRIHTGEKPYACLECGKRFS 132

  Fly   270 RKASLIIHMRQHTGEKPLQCGECKFSTRDPSVLHKHRQRHDSQDTRSSLK---CSQCDYFCIQAN 331
            ..::|:.|.|.||||||..|.:|..|......|.|||:.|      |.||   |.:|.....|..
Human   133 WSSNLMQHQRIHTGEKPYTCPDCGRSFTQSKSLAKHRRSH------SGLKPFVCPRCGRGFSQPK 191

  Fly   332 ALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQGLITNCEDSMDARAAGFKYPRKVG 396
            :|.||:||                          |.:....|:......:...||.|   |.:..
Human   192 SLARHLRL--------------------------HPELSGPGVAAKVLAASVRRAKG---PEEAV 227

  Fly   397 DKNGEISADCFMPLESVDSLPHEPALDTGGVTIPAPPSE 435
            ..:|||:.               |..|..|:.:...|.|
Human   228 AADGEIAI---------------PVGDGEGIIVVGAPGE 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	6/47 (13%)
		C2H2 Zn finger	261..281	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
ZNF787	NP_001002836.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..65		12/58 (21%)
		COG5048	<67..200	CDD:227381	41/164 (25%)
		C2H2 Zn finger	68..88	CDD:275368	5/19 (26%)
		C2H2 Zn finger	96..116	CDD:275368	0/19 (0%)
		C2H2 Zn finger	124..144	CDD:275368	7/19 (37%)
		C2H2 Zn finger	152..172	CDD:275368	7/19 (37%)
		C2H2 Zn finger	180..200	CDD:275368	8/45 (18%)
		C2H2 Zn finger	282..302	CDD:275368
		C2H2 Zn finger	319..339	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	357..382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100