DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11456 and Zbtb48

DIOPT Version :9

Sequence 1:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	XP_017175372.1	Gene:	Zbtb48 / 100090	MGIID:	2140248	Length:	767	Species:	Mus musculus

Alignment Length:	365	Identity:	73/365 - (20%)
Similarity:	120/365 - (32%)	Gaps:	132/365 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MENSARIVYVCSLCLRQYDLQEDLRGHLVYFHGYEPISTPSVKNKTAKTSTKEQTAAGSNSQDKQ 65
            :.::..:.|.||.|.:|:..::||:.|::..||     .|    |....|..:...:|.:...:.
Mouse   393 VSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHG-----AP----KPHAVSASQGWGSGGSGTAQS 448

  Fly    66 TVVERSENSEPPASELQPMPFKDFRLVLRANMLEP-CSFGKECPFKFQDATKMELHCSCHKGGSF 129
            .          |..::.|:|            :.| ||            ..:....|| .|.|:
Mouse   449 C----------PHLDVLPLP------------VSPTCS------------APLVPSASC-LGRSY 478

  Fly   130 SC--------------------------CEC------GME---------LPNWRRCSAHLWKAHQ 153
            ||                          |.|      ||:         :|:.||
Mouse   479 SCTRLLSIVEKSSLCVRNAGTGPRAATDCRCTSRPSTGMKGLMSVSSAAMPSPRR---------- 533

  Fly   154 VDVDLLVCPVFECNYKSPISALVWRHMQVHKKWRPRVLRSLAAVQRRRKLKEQSAEMAAQPAALP 218
                             |.|.....|...      |.|.|..:|.|....|.:.|:....|....
Mouse   534 -----------------PTSTCTCAHTPA------RSLSSATSVGRPSAPKVRQAQPLLAPGLRQ 575

  Fly   219 PSS----------KKNKYYAEK---TCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTAR 270
            |.|          |.|:.:..:   :||.|.::|.....|.:||.:.|.:.:|..|.:|||....
Mouse   576 PLSSTLSPIASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKA 640

  Fly   271 KASLIIHMRQHTGEKPLQCGECKFSTRDPSVLHKHRQRHD 310
            ...|.:|:|:|.|.:..:|.||.:.....:.|.:|.:.||
Mouse   641 VEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHD 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	7/20 (35%)
		C2H2 Zn finger	261..281	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..309	CDD:275368	5/19 (26%)
Zbtb48	XP_017175372.1	BTB_POZ_ZBTB48_TZAP_KR3	38..145	CDD:349541
		C2H2 Zn finger	316..336	CDD:275368
		zf-H2C2_2	328..351	CDD:372612
		C2H2 Zn finger	344..395	CDD:275368	0/1 (0%)
		zf-H2C2_2	387..410	CDD:372612	4/16 (25%)
		C2H2 Zn finger	403..424	CDD:275368	7/20 (35%)
		PHA03247	<426..583	CDD:223021	36/228 (16%)
		zf-H2C2_2	586..610	CDD:372612	5/23 (22%)
		C2H2 Zn finger	602..623	CDD:275368	7/20 (35%)
		C2H2 Zn finger	631..651	CDD:275368	7/19 (37%)
		zf-H2C2_2	644..668	CDD:372612	8/23 (35%)
		zf-C2H2	657..679	CDD:333835	5/21 (24%)
		C2H2 Zn finger	659..679	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100