DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CSN3 and COP13

DIOPT Version :9

Sequence 1:	NP_524190.2	Gene:	CSN3 / 40308	FlyBaseID:	FBgn0027055	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_568296.1	Gene:	COP13 / 831275	AraportID:	AT5G14250	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	148/461 - (32%)
Similarity:	226/461 - (49%)	Gaps:	61/461 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SALENYVNQVRTLSASGSYRELAEELPESLSLL---------------ARNWSILDNVLETLDMQ 52
            :::|..:..::.||.|          ||.||.|               ..|:|.||.    ||..
plant     6 NSVEAVITSIQGLSGS----------PEDLSALHDLLRGAQDSLRAEPGVNFSTLDQ----LDAS 56

  Fly    53 QHSLGVLYVLLAKLHSASTANPEPVQLIQLMRDFVQRNNNEQLRYAVCAFYETCHLFTEFVVQKN 117
            :||||.|| .|..|.....:..:....|.::..|:...:..|:|.|...|...|.:..:.|:...
plant    57 KHSLGYLY-FLEVLTCGPVSKEKAAYEIPIIARFINSCDAGQIRLASYKFVSLCKILKDHVIALG 120

  Fly   118 LSILGIRIISRAIDQIRQLETQLTPIHADLCLLSLKAKNFSVVLPYLDADITDISTVAAECKTQQ 182
            ..:.|:..:..|:.:::....:||.:|.|:..|.|:||::......|..||.:|
plant   121 DPLRGVGPLLNAVQKLQVSSKRLTALHPDVLQLCLQAKSYKSGFSILSDDIVEI----------- 174

  Fly   183 QQQSQHADANNDAKYFLLYFYYGGMIYTAVKNYERALYFFEVCITTPAMAMSHIMLEAYKKFLMV 247
                   |...|   |.||.||||||...:|.:::||......:|.|...::.|.||||||:::|
plant   175 -------DQPRD---FFLYSYYGGMICIGLKRFQKALELLYNVVTAPMHQVNAIALEAYKKYILV 229

  Fly   248 SLIVEGKIA-YIPKNTQVIG-RFMKPMANHYHDLVNVYANSSSEELRIIILKYSEAFTRDNNMGL 310
            |||..|:.. .:||...... |..|.....|.:|.|.|.:....||..:::..:..|..|.|:||
plant   230 SLIHNGQFTNTLPKCASTAAQRSFKNYTGPYIELGNCYNDGKIGELEALVVARNAEFEEDKNLGL 294

  Fly   311 AKQVATSLYKRNIQRLTKTFLTLSLSDVASRVQLASAVEAERYILNMIKSGEIYASINQKDGMVL 375
            .||..:|||||||.|||:.:|||||.|:|:.|||.:|.|||.::|.||:.|:|:|.||||||||.
plant   295 VKQAVSSLYKRNILRLTQKYLTLSLQDIANMVQLGNAKEAEMHVLQMIQDGQIHALINQKDGMVR 359

  Fly   376 FKDDPEKYNSPEMFLNVQNNITHVLDQVRQINKMEEEIILNPMYVKKALGSQ------DDDLTSQ 434
            |.:|||:|.|.||...:.:.|...:...:.:..|:|.:..:|:|:.| :|.:      .||..:.
plant   360 FLEDPEQYKSSEMIEIMDSVIQRTIGLSKNLLAMDESLSCDPLYLGK-VGRERQRYDFGDDFDTV 423

  Fly   435 HPKTFS 440
             |:.||
plant   424 -PQKFS 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN3	NP_524190.2	PCI	275..378	CDD:279707	52/102 (51%)
COP13	NP_568296.1	PINT	294..381	CDD:214509	49/86 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2248
eggNOG	1	0.900	-	-		E1_KOG2582
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2710
Inparanoid	1	1.050	208	1.000	Inparanoid score	I1265
OMA	1	1.010	-	-		QHG55351
OrthoDB	1	1.010	-	-		D929822at2759
OrthoFinder	1	1.000	-	-		FOG0005586
OrthoInspector	1	1.000	-	-		oto3148
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10758
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5221
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.940