DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R1 and Cnbd2

DIOPT Version :9

Sequence 1:	NP_001189150.1	Gene:	Pka-R1 / 40305	FlyBaseID:	FBgn0259243	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_081861.2	Gene:	Cnbd2 / 70873	MGIID:	1918123	Length:	673	Species:	Mus musculus

Alignment Length:	153	Identity:	39/153 - (25%)
Similarity:	71/153 - (46%)	Gaps:	15/153 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 IIQQGDEGDNFYVIDVGEVDV---------FVNSELVTTISEGGSFGELALIYGTPRAATVRAKT 301
            |:::|..|::||.|.:|.|.:         |::.. .|.:..||||||:.|:..|.|:|||....
Mouse   233 IVKKGQMGNSFYFIYLGTVAITEDEDGSSAFLDPH-PTLLHRGGSFGEMGLLSTTVRSATVVCME 296

  Fly   302 DVKLWGIDRDSYRRILMGSTIRKRKMYE-EFLSRVSILESL--DKWERLTVADSLETCSFDDGET 363
            :.:...:||:.:....:|..::|...|. .|...:.|.:|.  :|..:|.....:|..|:  |:.
Mouse   297 ETEFLVVDREDFVANKLGDEVQKETQYRYNFFRNLDIFQSWSEEKLWKLVALGRIERFSY--GQM 359

  Fly   364 IVKQGAAGDDFYIILEGCAVVLQ 386
            :.|..........|.:|...:|:
Mouse   360 VSKDFMNSAFITFICQGNCEILR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	Crp	213..>339	CDD:223736	29/102 (28%)
		CAP_ED	219..328	CDD:237999	26/90 (29%)
		Crp	331..>442	CDD:223736	12/58 (21%)
		CAP_ED	337..453	CDD:237999	11/52 (21%)
Cnbd2	NP_081861.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89
		Crp	200..>353	CDD:223736	32/120 (27%)
		CAP_ED	211..308	CDD:237999	24/75 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810