DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R1 and CG4839

DIOPT Version :9

Sequence 1:	NP_001189150.1	Gene:	Pka-R1 / 40305	FlyBaseID:	FBgn0259243	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	130/501 - (25%)
Similarity:	212/501 - (42%)	Gaps:	68/501 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QLSVNSIQDAVIDRFRSVA----LTTDANGAMRIRSFSEGVVATTHHHHQHQQNQQ-------QS 57
            :::||.|.|      .|||    ..|.::.::.....:||.|.....|.|....||       ||
  Fly   190 KVNVNGIID------ESVAHDDDYDTPSSNSIATTPVTEGPVKFFIGHTQELSAQQTDDTLSCQS 248

  Fly    58 PHCSGRGGRILRESSID--------GGVAMFDALLRDDHEHRLSLDAV-------HRMRHVRT-- 105
            ...:......|....:.        |......|..|......:||:.:       .|.|.|.|
  Fly   249 SDANNNSAAKLTNGVVPQEQPEREMGKQQALQAPPRAKSSSNVSLNYLAKSQTDSQRRRRVSTMP 313

  Fly   106 -----SCTTIPEEDAVSDRSLQIHLSTLAREREQELELERQREREEQVKLDASRQVISPDDCEDL 165
                 ....:|.|..|....|  ||........|:.:.:::::::::::.||:.........|:.
  Fly   314 DINIPPAPPLPPELLVPGTPL--HLRKKRSMERQQQQKQQEQQQQQEIQQDATNSQDQMAGAEES 376

  Fly   166 SPMPQTAAPPVRR-RGGISAEPVTEEDATNYVKKVVP-----------KDYKTMNALSKAIAKNV 218
            .....::.|...| .||:.           ||:...|           ||..|.|.:..||.:|.
  Fly   377 HKSSDSSTPKTHRVEGGLI-----------YVRPNFPIQSDIEIESIAKDEGTRNLIRTAIERND 430

  Fly   219 LFAHLDESERSD-IFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSF 282
            ...:|.:.||.: :.:||.|.::.....||::.:||...||...|:.||....:||.:......|
  Fly   431 FLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFGPATVF 495

  Fly   283 GELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERL 347
            ||||::|..||.|::.|.||.::|.|.|:::|.|:..|..|:|:...:||.....|:..|:...|
  Fly   496 GELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENLQFLRSAPFLQEFDQSLLL 560

  Fly   348 TVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEQGEDPAEVGRLGSSDYFGEIAL 412
            .|.|.|:...::....||::|..|::||||..| .|.:::..||.::.....| ...|||||.||
  Fly   561 KVVDLLQRKFYETDSCIVREGELGNEFYIIRCG-TVTIKKLDEQQQEQIVANR-KRGDYFGEQAL 623

  Fly   413 LLDRPRAATVVARGP-LKCVKLDRARFERVLGPCADILKRNITQYN 457
            |....|.|:|.|..| .:.:.|||..|...||....:.::..:|.|
  Fly   624 LNADVRQASVYADAPGTEVLMLDREAFISYLGTIKQLREKPSSQRN 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	Crp	213..>339	CDD:223736	42/126 (33%)
		CAP_ED	219..328	CDD:237999	37/109 (34%)
		Crp	331..>442	CDD:223736	38/111 (34%)
		CAP_ED	337..453	CDD:237999	38/116 (33%)
CG4839	NP_609349.1	Crp	428..577	CDD:223736	46/148 (31%)
		CAP_ED	431..539	CDD:237999	36/107 (34%)
		Crp	544..>650	CDD:223736	37/107 (35%)
		CAP_ED	550..663	CDD:237999	38/114 (33%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I744
eggNOG	1	0.900	-	-		E1_COG0664
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810