DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R1 and Pkg21D

DIOPT Version :9

Sequence 1:	NP_001189150.1	Gene:	Pka-R1 / 40305	FlyBaseID:	FBgn0259243	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_477213.1	Gene:	Pkg21D / 33253	FlyBaseID:	FBgn0000442	Length:	768	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	102/398 - (25%)
Similarity:	191/398 - (47%)	Gaps:	52/398 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 HRLSLDAVHRMRHVRTSCTTIPEEDAVSDRSLQIHLSTLAREREQEL--ELERQREREEQVKLDA 152
            ||    .:|:::.|....|          .:|.:..:..|:::...|  :...|..|.:...|.:
  Fly    40 HR----EIHKLKSVLQQTT----------NNLNVTRNEKAKKKLYSLPEQCGEQESRNQNPHLCS 90

  Fly   153 SRQVISPDDCE---------DLSPMPQT-----------------AAPPVRRRGGISAEPVTEED 191
            |..::.|...|         .|||:..|                 |.|...::.|:|||...:..
  Fly    91 SCGMVLPTSPEFALEALSLGPLSPLASTSSASPSGRTSADEVRPKAMPAAIKKQGVSAESCVQSM 155

  Fly   192 ATNYVKKVVP-----KDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGD 251
            ..:|   .:|     ||:.....:..||..|....::|.|:..::.|:|:..:..|||.:|::|:
  Fly   156 QQSY---SIPIPKYEKDFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGE 217

  Fly   252 EGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKTD-VKLWGIDRDSYRR 315
            .|.:.||...||..|....:::..:..|.:|||||::|...|.|::|..:: .::|.:||..:::
  Fly   218 VGAHLYVSAAGEFAVMQQGKVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQ 282

  Fly   316 ILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEG 380
            |:|.:.:::.:....||..|.:|.:|.:.....:||.||...:..|..|::||.|||.|::|.:|
  Fly   283 IMMCTGLQRIENSVNFLRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQG 347

  Fly   381 CAVVLQQRSEQGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGP-LKCVKLDRARFERVLGP 444
            ...|.|:.:....:..|:..|...|||||.||:.:..|.|.::|..| ::|:.|||..|:|::|.
  Fly   348 NVRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGVECLTLDRDSFKRLIGD 412

  Fly   445 CADILKRN 452
            ..::.:::
  Fly   413 LCELKEKD 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	Crp	213..>339	CDD:223736	36/126 (29%)
		CAP_ED	219..328	CDD:237999	30/109 (28%)
		Crp	331..>442	CDD:223736	40/111 (36%)
		CAP_ED	337..453	CDD:237999	38/117 (32%)
Pkg21D	NP_477213.1	Crp	183..386	CDD:223736	61/202 (30%)
		CAP_ED	185..285	CDD:237999	29/99 (29%)
		CAP_ED	304..419	CDD:237999	38/114 (33%)
		Pkinase	457..717	CDD:278497
		STKc_cGK	463..724	CDD:270724
		S_TK_X	719..>760	CDD:214529
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I744
eggNOG	1	0.900	-	-		E1_COG0664
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810