Protein Alignment Pka-R1 and Prkar2b

DIOPT Version :10

• Sequence 1: NP_001189150.1
• Gene: Pka-R1 / 40305
• FlyBaseID: FBgn0259243
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_001025191.1
• Gene: Prkar2b / 24679
• RGDID: 3394
• Length: 416
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 125/299 - (41%)
• Similarity: 179/299 - (59%)
• Gaps: 17/299 - (5%)

  Fly   173 APPVR---RRGGISAEPVT----EEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSD 230
            ||.:.   ||..:.||...    |:||.:.:  :.||.....|.|.:|....:||.:||..:.|.
  Rat   101 APVINRFTRRASVCAEAYNPDEEEDDAESRI--IHPKTDDQRNRLQEACKDILLFKNLDPEQMSQ 163

  Fly   231 IFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSE----LVTTISEGGSFGELALIYGT 291
            :.||||......||::|.|||:||||||||.|..|::|..:    .|......||||||||:|.|
  Rat   164 VLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNT 228

  Fly   292 PRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETC 356
            |||||:.|.:...|||:||.::|||::.:..:||||||.|:..:..|:||:..|||.|.|.:.|.
  Rat   229 PRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTK 293

  Fly   357 SFDDGETIVKQGAAGDDFYIILEGCAVVLQQR---SEQGEDPA-EVGRLGSSDYFGEIALLLDRP 417
            .::|||.|:.||.:.|.|:|:..|...:..:|   |:..|:.| |:.|.....||||:||:.::|
  Rat   294 VYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGELALVTNKP 358

  Fly   418 RAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQY 456
            |||:..|.|.:||:.:|...|||:||||.:|:||||..|
  Rat   359 RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	CAP_ED	219..328	CDD:237999	54/112 (48%)
		CAP_ED	337..453	CDD:237999	50/119 (42%)
Prkar2b	NP_001025191.1	Dimerization and phosphorylation	2..151		14/51 (27%)
		DD_RIIbeta_PKA	3..45	CDD:438525
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..97
		CAP_ED	152..265	CDD:237999	54/112 (48%)
		CAP_ED	274..394	CDD:237999	50/119 (42%)