Protein Alignment Pka-R1 and Pnpla7

DIOPT Version :9

• Sequence 1: NP_001189150.1
• Gene: Pka-R1 / 40305
• FlyBaseID: FBgn0259243
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_653339.2
• Gene: Pnpla7 / 246246
• RGDID: 708466
• Length: 1349
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 86/444 - (19%)
• Similarity: 155/444 - (34%)
• Gaps: 113/444 - (25%)

  Fly    51 QQNQQQSPHCSGRGGRILRESSIDGGVAMFDALLRDDHEHRLSLDAVH----RMRHVR-----TS 106
            ::..::||..|.      ..||....||:...||:  ....:.|..:|    .:|..:     ||
  Rat   345 EEQLERSPRLSE------FNSSDQRSVAVSGPLLK--RSCSVPLPPIHGEIDELRQAQGSGSNTS 401

  Fly   107 CTTIPEEDAVSDRSLQIHLSTLAREREQELELERQREREEQVKLDASRQVISPDDCEDLSPMPQT 171
            .....:|.|.||..:..:.:.:....|::|......:.::.|..:.|...       ..|..|:.
  Rat   402 AFQESQEGATSDLGMAYNRARILPHSEEQLGSSLASKSKKSVVAETSAVF-------HYSEKPRD 459

  Fly   172 AAPPVRRRGGISAEPVTEEDATNYVKKVVPKDYKTMNALS--KAIAKNVLFAHLDESERSDIFDA 234
            ...|..|              |:.:.:...||..|:..|.  ..:...|.|.|:.
  Rat   460 EPGPSGR--------------TDAIFRAATKDLLTLMKLDDPSLLDGRVAFLHVP---------- 500

  Fly   235 MFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISE--------GGSFGELALIYGT 291
                   ||..:.:|||:..|...:..|.:.|:  .:.:.::.:        |...|:||::.|.
  Rat   501 -------AGTIVSKQGDQDVNILFVVSGMLHVY--QQKIDSLEDTCLFLTHPGEMVGQLAVLTGE 556

  Fly   292 PRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKR------------KMYEEFLSRVSILESLDKW 344
            |...|:||..|.....|.:..:..|:     |||            :....|:.::..
  Rat   557 PLMFTIRANRDCSFLSISKAHFYEIM-----RKRPDVVLGVAHTVVRRMSSFVRQIDF------- 609

  Fly   345 ERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEQGEDPAE---VGRLGSSDY 406
                   :|:....:.|..|.:||...|..||:|.|     :.||...:|..:   .|..|..|.
  Rat   610 -------ALDWMEVEAGRAIYRQGDKSDCTYIVLSG-----RLRSVIRKDDGKKRLAGEYGRGDL 662

  Fly   407 FGEIALLLDRPRAATV-------VARGPLKCVKLDRARFERVLGPCADILKRNI 453
            .|.:.:|..:.||.||       :|:.|...:...:.|:.:|:.....:|...|
  Rat   663 VGVVEMLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKI 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	Crp	213..>339	CDD:223736	27/145 (19%)
		CAP_ED	219..328	CDD:237999	25/128 (20%)
		Crp	331..>442	CDD:223736	26/120 (22%)
		CAP_ED	337..453	CDD:237999	27/125 (22%)
Pnpla7	NP_653339.2	Crp	164..>306	CDD:223736
		CAP_ED	170..291	CDD:237999
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..361		4/21 (19%)
		Crp	478..>607	CDD:223736	29/152 (19%)
		CAP_ED	478..588	CDD:237999	28/133 (21%)
		Crp	600..>729	CDD:223736	29/136 (21%)
		CAP_ED	601..709	CDD:237999	27/126 (21%)
		Involved in the binding to lipid droplets. /evidence=ECO:0000250|UniProtKB:A2AJ88	678..964		7/39 (18%)
		Pat_PNPLA6_PNPLA7	930..1235	CDD:132864
		RssA	935..1221	CDD:224666
		GXGXXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	951..956
		GXSXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	978..982
		DGA/G. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	1100..1102
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1297..1349

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900