DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pka-R1 and Pnpla7

DIOPT Version :10

Sequence 1:NP_001189150.1 Gene:Pka-R1 / 40305 FlyBaseID:FBgn0259243 Length:464 Species:Drosophila melanogaster
Sequence 2:XP_036017642.1 Gene:Pnpla7 / 241274 MGIID:2385325 Length:1384 Species:Mus musculus


Alignment Length:450 Identity:90/450 - (20%)
Similarity:156/450 - (34%) Gaps:117/450 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 RLSLDAVHRMRHVRTSCTTIPEEDAVSDRSLQIHLSTLAREREQ-----ELELERQREREEQVKL 150
            |::..|:|....:.|.... ||..|:...|:   .|...|.:.|     |.:|||.....|....
Mouse   303 RVTFLALHNYLGLTTELFN-PESQAIPLLSV---ASVAGRAKRQMSYGPEEQLERSLRPSEFSSS 363

  Fly   151 DASRQVISPD------DCEDLSPMPQTAAPPVRRRGG----ISAEPVTEEDATNYV------KKV 199
            |.....::..      .|....|........:|:..|    .||...:.|.||:.:      .::
Mouse   364 DHGSSCVTVSGPLLKRSCSVPLPSNHGEVDELRQSQGSGSNTSAFQESHEGATSDLGMAYNRARI 428

  Fly   200 VP-KDYKTMNALSKAIAKNVL------FAHLDESERSD--------------------------- 230
            :| .|.:..|:|:....|:|:      ..|..|:.|.:                           
Mouse   429 LPHSDEQLGNSLASKSKKSVVAETPSAIFHYSENFRDETGACGKTDAIFRAATKDLLTLMKLDDP 493

  Fly   231 -IFDAMFPVNHI-AGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISE--------GGSFGEL 285
             :.|......|: ||..:.:|||:..|...:..|.:.|:  .:.:.::.:        |...|:|
Mouse   494 SLLDGRVAFLHVPAGTLVSKQGDQDVNILFVVSGMLHVY--QQKIDSLEDTCLFLTHPGEMVGQL 556

  Fly   286 ALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKR------------KMYEEFLSRVSIL 338
            |::.|.|...|:||..|.....|.:..:..|:     |||            |....|:.::.. 
Mouse   557 AVLTGEPLMFTIRANRDCSFLSISKAHFYEIM-----RKRPDVVLGVAHTVVKRMSSFVRQIDF- 615

  Fly   339 ESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEQGEDPAE---VGR 400
                         :|:....:.|..|.:||...|..||:|.|     :.||...:|..:   .|.
Mouse   616 -------------ALDWMEVEAGRAIYRQGDKSDCTYIVLSG-----RLRSVIRKDDGKKRLAGE 662

  Fly   401 LGSSDYFGEIALLLDRPRAATV-------VARGPLKCVKLDRARFERVLGPCADILKRNI 453
            .|..|..|.:..|..:.||.||       :|:.|...:...:.|:.:|:.....:|...|
Mouse   663 YGRGDLVGVVETLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKI 722

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pka-R1NP_001189150.1 CAP_ED 219..328 CDD:237999 29/163 (18%)
CAP_ED 337..453 CDD:237999 27/125 (22%)
Pnpla7XP_036017642.1 CAP_ED 170..294 CDD:237999
CAP_ED 484..594 CDD:237999 25/116 (22%)
CAP_ED 607..715 CDD:237999 27/126 (21%)
Pat_PNPLA6_PNPLA7 944..1249 CDD:132864
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.