Protein Alignment Pka-R1 and Prkar2a

DIOPT Version :10

• Sequence 1: NP_001189150.1
• Gene: Pka-R1 / 40305
• FlyBaseID: FBgn0259243
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_032950.1
• Gene: Prkar2a / 19087
• MGIID: 108025
• Length: 402
• Species: Mus musculus
• Alignment Length: 314
• Identity: 124/314 - (39%)
• Similarity: 182/314 - (57%)
• Gaps: 20/314 - (6%)

  Fly   158 SPDDCEDLS---PMPQTAAPPVRRRGGISAEPVT--EEDATNYVKKVVPKDYKTMNALSKAIAKN 217
            |..|.||..   |:|.    ...||..:.||...  ||:..|..:.|.||..:....|.:|....
Mouse    75 SDSDSEDADLEVPVPS----KFTRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDI 135

  Fly   218 VLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEG--- 279
            :||.:||:.:.|.:.||||.......|::|.|||:|||||||:.|..|:.|..:..|. |.|
Mouse   136 LLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTR-SVGQYD 199

  Fly   280 --GSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLD 342
              ||||||||:|.||||||:.|.::..|||:||.::|||::.:..:||||:|.|:..|.:.:||:
Mouse   200 NRGSFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLE 264

  Fly   343 KWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEG-CAVVLQQRSEQ----GEDPAEVGRLG 402
            ..||:.:.|.:....:.|||.|:.||...|.||||..| .:::::.:::.    |....|:....
Mouse   265 MSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCH 329

  Fly   403 SSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQY 456
            ...||||:||:.::||||:..|.|.:||:.:|...|||:||||.||:||||:.|
Mouse   330 KGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHY 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	CAP_ED	219..328	CDD:237999	54/113 (48%)
		CAP_ED	337..453	CDD:237999	45/120 (38%)
Prkar2a	NP_032950.1	DD_RIIalpha_PKA	4..44	CDD:438524
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..84		4/8 (50%)
		CAP_ED	137..249	CDD:237999	53/112 (47%)
		CAP_ED	259..380	CDD:237999	45/120 (38%)