DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R1 and M110.7

DIOPT Version :9

Sequence 1:	NP_001189150.1	Gene:	Pka-R1 / 40305	FlyBaseID:	FBgn0259243	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_495734.3	Gene:	M110.7 / 187474	WormBaseID:	WBGene00010915	Length:	1095	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	48/241 - (19%)
Similarity:	85/241 - (35%)	Gaps:	57/241 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 ERSDIFDAMFPVNHIAGENIIQQGD-EGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYG 290
            |.|...|.:|.|   .|:..:::|| |.|     |.|       :.|...:..|.....:.::..
Worm   340 ENSFEIDMIFVV---FGKLRLKRGDLEHD-----DTG-------TSLTFDVYPGDMLPSMQILTN 389

  Fly   291 TPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVS----ILESLDKWERLTVAD 351
            .|...:.:|......:.|.||.|.:.|....:...::....|..:|    :.:....|.|:
Worm   390 EPAMCSAKALEKTIYFKICRDEYIQFLFAHPVIYLRLAFHALQFISPFARVFDMAVHWHRI---- 450

  Fly   352 SLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEQGEDPAEVGRLGSSDYFGEIALLLDR 416
                   :.|:.:.:||...|..:|::.|       |....:....:...|..|..|...:...|
Worm   451 -------ETGQALFRQGDKSDSMHIVMGG-------RLRAVDSTKIIEEYGRLDLIGITDMAEKR 501

  Fly   417 PRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNSFVSL 462
            ||..||:|           .||..::  |   :..|:.   |||.:
Worm   502 PRRNTVMA-----------VRFSHIV--C---IPENLL---SFVKI 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R1	NP_001189150.1	Crp	213..>339	CDD:223736	23/116 (20%)
		CAP_ED	219..328	CDD:237999	21/101 (21%)
		Crp	331..>442	CDD:223736	22/114 (19%)
		CAP_ED	337..453	CDD:237999	21/115 (18%)
M110.7	NP_495734.3	CAP_ED	316..427	CDD:237999	21/101 (21%)
		Crp	325..>432	CDD:223736	21/106 (20%)
		Crp	423..>543	CDD:223736	27/143 (19%)
		CAP_ED	444..538	CDD:237999	25/122 (20%)
		Patatin_and_cPLA2	752..1040	CDD:299702
		RssA	756..1046	CDD:224666
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900