Protein Alignment HIPP1 and fadJ

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_416843.1
• Gene: fadJ / 949097
• ECOCYCID: G7212
• Length: 714
• Species: Escherichia coli
• Alignment Length: 781
• Identity: 138/781 - (17%)
• Similarity: 243/781 - (31%)
• Gaps: 284/781 - (36%)

  Fly     3 QVSDSAVTTLESTQAEEPPPGVEKVETLELKTAA-----LETLSE----------SAGP------ 46
            ::.:.||.|::       .|| ||:.||:.:.|:     ::.|.|          ||.|
E. coli    12 RLDNIAVITID-------VPG-EKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAG 68

  Fly    47 TDLENELANLNGSEEGPGLDELSTLEREIAKLHNIRPPDAASEVKDS----DTPIALADNGGLEP 107
            .|: |.:.|...::|...|....  ::.:|::|.: |....:.:..:    ...:|||.:|
E. coli    69 ADI-NMIGNCKTAQEAEALARQG--QQLMAEIHAL-PIQVIAAIHGACLGGGLELALACHG---- 125

  Fly   108 RQAPDEAK--CRTPIIEEGNAASGNGQSSESPLEEVDLIALLKGTDTSHDQPTGEEKCTLEKALS 170
            |...|:.|  ...|.::.| ...|:|.:...|        .|.|..|:.:.....::...::||.
E. coli   126 RVCTDDPKTVLGLPEVQLG-LLPGSGGTQRLP--------RLIGVSTALEMILTGKQLRAKQALK 181

  Fly   171 ELDGVGEDGDV---GVTIEGEGQFEIMEIDDDE----------------------GESSSRKASP 210
                :|...||   .:.:|...:....|.....                      |:.:..|...
E. coli   182 ----LGLVDDVVPHSILLEAAVELAKKERPSSRPLPVRERILAGPLGRALLFKMVGKKTEHKTQG 242

  Fly   211 KVPASKPIKSNSLPSISKHKLSPEQARAVALEQMAGLKPKSR------------RKE-----PPA 258
            ..||::.|.......:::...|...|.|.|..::| :.|:|:            :|:     |||
E. coli   243 NYPATERILEVVETGLAQGTSSGYDAEARAFGELA-MTPQSQALRSIFFASTDVKKDPGSDAPPA 306

  Fly   259 PPSVVA-----------------------------PIDIVSSLNDDWDDYD----------SEED 284
            |.:.|.                             |..|..:|...||..:          ||.|
E. coli   307 PLNSVGILGGGLMGGGIAYVTACKAGIPVRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERD 371

  Fly   285 KSAS-----------------------------ALVTEVITLPSAHVV--TKKPPLPVKKLSSPV 318
            |..:                             .:|.||....:||.:  :....||:..:::
E. coli   372 KQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAA-- 434

  Fly   319 KHS--PNSAILLN-----NKISGVKVMLKTVSQKQLAASTGAAAEKTKPTVVVSPPKETEEHTTG 376
             |:  |...|.|:     .|:..|:::....:..|..|:|...|:|...|.:|...|      .|
E. coli   435 -HATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDK------AG 492

  Fly   377 FKRMRVIKRKIIWDPDVPETKKSFAQYASTKAACPA------PTTPKTTVKSISPTTTTK----K 431
            |...|::.      |.:.|..:...|....:....|      |..|...:..:...|.||    .
E. coli   493 FYVNRILA------PYINEAIRMLTQGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVL 551

  Fly   432 EVAPKKRSATPTARSTKAGTPVGGTERGPSPVKRRAQTPNTGLANG---------GTQKKKKVS- 486
            |.|..:|.:.|.                 :.|.........|..||         |.:.||:|.
E. coli   552 EAAYGERFSAPA-----------------NVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDP 599

  Fly   487 EIDRLMGDEGAANMIHAVEHEQRELSGGEVSNKPLMRKRAMTITGRNQAARVAVEPT-------- 543
            .|..|:|.:|           |..:|..:|:.:.:|..       .|:|.|...|..
E. coli   600 AIYPLIGTQG-----------QGRISAPQVAERCVMLM-------LNEAVRCVDEQVIRSVRDGD 646

  Fly   544 ---------PP---------------------KKESAQSAAKRTPADSVFTKATANTSARKPRAS 578
                     ||                     ::.:.|..::.||.:.:........|..|..|:
E. coli   647 IGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMGARGESFWKTTAT 711

  Fly   579 D 579
            |
E. coli   712 D 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628	102/609 (17%)
		crotonase-like	673..870	CDD:119339
fadJ	NP_416843.1	fadJ	1..708	CDD:236864	135/775 (17%)