DRSC/TRiP Functional Genomics Resources

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Protein Alignment HIPP1 and DCI1

DIOPT Version :10

Sequence 1:NP_649261.1 Gene:HIPP1 / 40302 FlyBaseID:FBgn0037027 Length:926 Species:Drosophila melanogaster
Sequence 2:NP_014823.3 Gene:DCI1 / 854352 SGDID:S000005706 Length:271 Species:Saccharomyces cerevisiae


Alignment Length:280 Identity:59/280 - (21%)
Similarity:91/280 - (32%) Gaps:82/280 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   668 SELVCLH--------KVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTV- 723
            |..||.|        |:....||...|..   ...|...||.:.||          .::||.|| 
Yeast     2 SSRVCYHINGPFFIIKLIDPKHLNSLTFE---DFVYIALLLHKAND----------IDSVLFTVL 53

  Fly   724 --EGPQFCQG---IDCQELIQGSLEKRKDSASQLAVALKC----YLRTLATFPKPLVAGIVGSQI 779
              .|..|..|   ....:|..|.:....:..|:|..|:..    .....|...|.||..:.|..|
Yeast    54 QSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAI 118

  Fly   780 NLGVMQLPFADYVVASDDCSFET-NYAKLGQLPE-----------GYALWHGHQRVSSEVHSRLF 832
            .|....:...|.|.:.:|..|.. .::.||.:.|           |....:.|...|:.|   ||
Yeast   119 GLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPV---LF 180

  Fly   833 LMGERLFAT------ELLESNSFVDKICKARNVN--------------------EMALAKAKQIS 871
               :.|..|      :|..:.:|.:|:.:....|                    :..|.||:.:.
Yeast   181 ---KELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAME 242

  Fly   872 T-------SSAEMYRTLKKL 884
            |       :|.|.::..|:|
Yeast   243 TNGTLPFWASGEPFKRFKQL 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HIPP1NP_649261.1 PTZ00449 <148..580 CDD:185628
crotonase-like 673..870 CDD:119339 51/252 (20%)
DCI1NP_014823.3 crotonase-like 7..178 CDD:119339 39/183 (21%)
Blue background indicates that the domain is not in the aligned region.

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