Protein Alignment HIPP1 and Echdc1

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: XP_006512860.1
• Gene: Echdc1 / 52665
• MGIID: 1277169
• Length: 374
• Species: Mus musculus
• Alignment Length: 353
• Identity: 74/353 - (20%)
• Similarity: 126/353 - (35%)
• Gaps: 92/353 - (26%)

  Fly   617 NRPGAANLSDDAGEGSDPSFKFVKPVSKSSQRG---GEDTSSHTLANDMKANNGSELV-CL---- 673
            |||||.                .||....:||.   |:..|.|..|:..:.....|:. ||
Mouse    36 NRPGAV----------------WKPEEARAQRKVGCGKRVSGHGSASQSQGLRAGEMAKCLLTSS 84

  Fly   674 ----HKVNKVAHLVIHTERGNFGHTYSKQLLEQLND---------------TLSSVARKGEFNTV 719
                .|:.:....:.:|..| |.....|::|||...               ||::..:...|:.|
Mouse    85 LSVRTKLLQTGVSLYNTSHG-FHEEEVKKILEQFPGGSIDLLKKQNGIGILTLNNPNKMNAFSGV 148

  Fly   720 L-------------------LTVEGPQ--FCQGIDCQELIQGSLEKRKDSASQLAVALKCYLR-T 762
            :                   |.:.|.:  ||.|.|...:       :..|..:..|||..::: |
Mouse   149 MMLQLLERVIELENWTEGKGLIIHGAKNTFCSGSDLNAV-------KALSTPESGVALSMFMQNT 206

  Fly   763 LATFPK-PL--VAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLGQLPEGYALWHGHQRVS 824
            |..|.: ||  ||.:.|..:..|.......|:.:.:::......:.::|.:|.    |.|..|:.
Mouse   207 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPS----WGGTSRLV 267

  Fly   825 SEVHSRLFLMGERLFATELLESN-----SFVDKICKARNVNEMALAKAKQ----ISTSSAEMYRT 880
            ..:.||..|  :.|..|..|:|.     ...|::.:..: ...||.:|::    ..:...::.|.
Mouse   268 EIIGSRQAL--KVLSGTLKLDSKEALNIGLTDEVLQPSD-ETTALEQAQEWLEKFVSGPPQVIRG 329

  Fly   881 LKKLNHSAVNVTKFPRLDEELKVIGEQW 908
            |||...||..:.....|..|..|:...|
Mouse   330 LKKSVCSARELYIEEALQNERDVLETLW 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628
		crotonase-like	673..870	CDD:119339	49/253 (19%)
Echdc1	XP_006512860.1	CaiD	124..367	CDD:440647	50/248 (20%)