Protein Alignment HIPP1 and Echdc1

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: XP_006227808.3
• Gene: Echdc1 / 361465
• RGDID: 1359654
• Length: 466
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 104/494 - (21%)
• Similarity: 178/494 - (36%)
• Gaps: 100/494 - (20%)

  Fly   448 KAGTPVGGTERGPSPVKRRAQTPNTGLANGGTQKKKKVSEIDRLMGDEGAANMIHAVEHEQRELS 512
            |.|: :.|.|.||...|:..:...:         :|:|:...|...:..|.|       .::::.
  Rat    23 KTGS-IPGAETGPQQGKQAGEPSGS---------RKRVARSGRWGAERRAQN-------TEKDIR 70

  Fly   513 GGEVSNKPLMRKRA---MTITGRNQAARVAVEPTPPKKESAQSAAKRTPADSVFTKATANTSARK 574
            |.  ..:|:...||   :..:||.|....|..|.|......:..:.|.|     ::..|...:..
  Rat    71 GR--GCRPVCAYRAAVRLRPSGRPQRCPPAPAPQPCGVIGEERLSGRIP-----SRGGARLRSGS 128

  Fly   575 PRASDS----WDYVYKQRASEESMIMR------RR-----SNSSYSSNASVSRNSLDNRPGAANL 624
            |....:    |..|...|:.....|:.      ||     :.|..:|:.||....|.......|.
  Rat   129 PLGRTALCRLWTAVQAPRSRWAREILEVSGGALRRYREEMAKSLLASSLSVRTKILQTGVSLYNT 193

  Fly   625 SDDAGEGSDPSFKFVKPVSKSSQRGGEDTSSHTLANDMKANNGSELVCLHKVNKVAHLVIHTERG 689
            :....|      :.||.:.:....|..|.        .|..||..::.|:..||:         .
  Rat   194 THGFHE------EEVKKILEQFPGGSIDL--------QKKQNGIGILTLNNSNKM---------N 235

  Fly   690 NFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTVEGPQ--FCQGIDCQELIQGSLEKRKDSASQL 752
            .|......||||::.:..:....||      |.|.|.:  ||.|.|...:       :..|..:.
  Rat   236 AFSGAMMLQLLERVIELENWTEGKG------LIVHGAKNTFCSGSDLNAV-------KALSTPEN 287

  Fly   753 AVALKCYLR-TLATFPK-PL--VAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLGQLPEG 813
            .|||..::: ||..|.: ||  ||.:.|..:..|.......|:.:.:::......:.::|.:|.
  Rat   288 GVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPS- 351

  Fly   814 YALWHGHQRVSSEVHSRLFLMGERLFATELLESN-----SFVDKICKARNVNEMALAKA----KQ 869
               |.|..|:...:.||..|  :.|..|..|:|.     ...|::.:..: ...||.:|    :|
  Rat   352 ---WGGASRLVEIIGSRQAL--KVLSGTFKLDSKEALRIGLADEVLQPSD-EATALEQAQEWLEQ 410

  Fly   870 ISTSSAEMYRTLKKLNHSAVNVTKFPRLDEELKVIGEQW 908
            ..:..|::.|.|||...|...:.....|..|..|:...|
  Rat   411 FVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLW 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628	26/134 (19%)
		crotonase-like	673..870	CDD:119339	47/211 (22%)
Echdc1	XP_006227808.3	None