Protein Alignment HIPP1 and Cdyl

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: XP_017456089.1
• Gene: Cdyl / 361237
• RGDID: 1549745
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 743
• Identity: 132/743 - (17%)
• Similarity: 253/743 - (34%)
• Gaps: 194/743 - (26%)

  Fly   232 SPEQARAVALEQMAGLKPKSRRKEPPAPPSVVAPIDIVSSLNDD--------------------- 275
            |.::|....|::.........|::..|.|:.|:..|.||....|
  Rat     9 STKEAEPCTLQEKEEHPVDDTRQQNNAVPATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEY 73

  Fly   276 ---WDDYDSEEDKSASALVTEVITLPSAHVVTKKPPL-----------PVKKLSSPVKHSPNSAI 326
               |..||||:|...          |..|:|..:..:           ....|:...:.||::|
  Rat    74 LVRWKGYDSEDDTWE----------PEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNA- 127

  Fly   327 LLNNKISGVKVMLKTVSQKQLAASTGAAAEKTKPTVVVSPPKETEEHTTGFKRMRVIKRKIIWDP 391
                             :||::.||.:|..||.|..:| ..|:.|..|.
  Rat   128 -----------------RKQISRSTHSALSKTNPKALV-VGKDHESKTN---------------- 158

  Fly   392 DVPETKKSFAQYASTKAACPAPTTPK-TTVKSISPTTTTKKEVAPKKRSATPTARSTKAGTPVGG 455
                      |..:|.......|.|. ...|::....:..|.:.||.        ..|..|.:.|
  Rat   159 ----------QLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKS--------PIKGRTSIDG 205

  Fly   456 TERGPSPVKR------------RAQTPNTGLANGGTQKKKKVSEIDRLMGDEGAANMIHAVEHEQ 508
            . .|.||.|.            .|:.|...|...|.::.:.           |:...||::   .
  Rat   206 F-HGESPEKLDQGAEDTVTPEVTAEKPTGALLGPGAERARM-----------GSRPRIHSL---V 255

  Fly   509 RELSGGEVSNKPLMRKRAMTITGRNQAARVAVEPTPPKKESAQSAAKRTPADSVFTKATANTSAR 573
            .::||      |:....|.|:....:.:..:      .|||.:.:...:.....::..:..||
  Rat   256 PQVSG------PVTAAMATTLAVNGKGSLCS------SKESCEVSCPFSLLRLFYSCVSQGTS-- 306

  Fly   574 KPRASDSWDYVYKQRASEESMIMRRRSNSSYSSNASVSRNSLDNRPGAANLSDDAGEGSDPSFKF 638
                               ..:....:|.:.:...||:..:...|                  ||
  Rat   307 -------------------PFMDALTANGTVTIQTSVTGVTAGKR------------------KF 334

  Fly   639 V-----KPVSKSSQRGGEDTSSHTLANDMKANNGSELVCLHKVNKVAHLVIHTERGNFGHTYSKQ 698
            :     :|..|..:.....|.|.....|         :.:.|.:...|:::.| :.:..::.:.:
  Rat   335 IDDRRDQPFDKRLRFSVRQTESAYRYRD---------IVVRKQDGFTHILLST-KSSENNSLNPE 389

  Fly   699 LLEQLNDTLSSVARKGEFNTVLLTVEGPQFCQGIDCQELIQGSLEKRKDSASQLAVALKCYLRTL 763
            :::::...||:.| ..:...|||:..|..||.|:|....|:...:.||..::::|.|::.::.|.
  Rat   390 VMKEVQSALSTAA-ADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTF 453

  Fly   764 ATFPKPLVAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLGQLPEGYALWHGHQRVSSEVH 828
            ..|.||::..:.|..|.||...||..|.|.|::...|:|.|...||.|:|.:.....:.:.....
  Rat   454 IQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASA 518

  Fly   829 SRLFLMGERLFATELLESNSFVDKICKARNVNEMALAKAKQISTSSAEMYRTLKKLNHSAVNVTK 893
            :.:.|.|.:|.|.|.. ....|.::.......:..:.:.|::::.:..:....|.|....:.:..
  Rat   519 NEMLLSGRKLTAQEAC-GKGLVSQVFWPGTFTQEVMVRIKELASCNPIVLEESKALVRCNMKMEL 582

  Fly   894 FPRLDEELKVIGEQWVTADCLANFKRYL 921
            ....:.|...:.:.|.:|..:.:..:||
  Rat   583 EQANERECDALKKIWGSAQGMDSMLKYL 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628	68/395 (17%)
		crotonase-like	673..870	CDD:119339	46/196 (23%)
Cdyl	XP_017456089.1	CD_CDY	56..105	CDD:349284	9/58 (16%)
		crotonase-like	363..559	CDD:119339	46/198 (23%)