back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HIPP1 and Cdyl2

DIOPT Version :10

Sequence 1:	NP_649261.1	Gene:	HIPP1 / 40302	FlyBaseID:	FBgn0037027	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	XP_017456726.1	Gene:	Cdyl2 / 292044	RGDID:	1309548	Length:	551	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	93/459 - (20%)
Similarity:	200/459 - (43%)	Gaps:	50/459 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   499 NMIHAVEHEQRELSGGEVSNKPLMR-KRAMTITGRNQAARVAVEPTPPKKESAQSAAKRTPADSV 562
            |.:| :..:::..||.:.....|:| .|::.:      .|::..|..|.| |..::.||...:|.
  Rat   104 NGLH-LPKDKKVKSGKQAGASKLLRDARSLPV------ERLSHRPLEPGK-SKSTSHKRKRVNSP 160

  Fly   563 FTKATANTSARKP-RASDSWDYVYKQRASE---ESMIMRRRSNSSYSSNASVSRN---------- 613
            .:::...:|.:.| ||:.:..|    |.:.   :.|.:::..|...:.:|...::
  Rat   161 LSRSKKGSSGKAPDRATKTVSY----RTTPSGLQIMPLKKAQNGLENGDAGSEKDESHFGNGSHQ 221

  Fly   614 ---SLDNRPGAANLSD---------DAGEGS---DPSFKFVKPVSKSSQRGGEDTSSHTLANDMK 663
               .|:::.|....||         :.|.||   :.......||.:..:...:......|...::
  Rat   222 PDLELNDQLGEQETSDCDGTHSALVENGIGSALTNGGLNLHSPVKRKLETEKDYVFDKRLRYSVR 286

  Fly   664 ANNGS---ELVCLHKVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTVEG 725
            .|..:   ..:.:.|.....|:::.::..: .:..:.::::::...|.:.| ..:...:||:..|
  Rat   287 QNESNCRFRDIVVRKEEGFTHILLSSQTSD-NNALTPEIMKEVRRALCNAA-TDDSKLLLLSAVG 349

  Fly   726 PQFCQGIDCQELI-QGSLEKRKDSASQLAVALKCYLRTLATFPKPLVAGIVGSQINLGVMQLPFA 789
            ..||.|:|...|| :.|.::||:| :::|.|::.:::....|.||:|..|.|..:.||...||..
  Rat   350 SVFCSGLDYSYLIGRLSSDRRKES-TRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLC 413

  Fly   790 DYVVASDDCSFETNYAKLGQLPEGYALWHGHQRVSSEVHSRLFLMGERLFATELLESNSFVDKIC 854
            |.|.||:...|:|.||.:...|.|.:.:...|.:...:.:.:...|.:|.|.|.. |...|.::.
  Rat   414 DIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEAC-SRGLVSQVF 477

  Fly   855 KARNVNEMALAKAKQISTSSAEMYRTLKKLNHSAVNVTKFPRLDEELKVIGEQWVTADCLANFKR 919
            .....::..:.:.|::::.||.:....|.|..|.:........::|..::.:.|.::..|.:...
  Rat   478 WPTTFSQEVMLRVKEMASCSAVVLEDSKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFS 542

  Fly   920 YLND 923
            ||.|
  Rat   543 YLQD 546

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.