Protein Alignment HIPP1 and Hibch

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_666220.1
• Gene: Hibch / 227095
• MGIID: 1923792
• Length: 385
• Species: Mus musculus
• Alignment Length: 294
• Identity: 61/294 - (20%)
• Similarity: 113/294 - (38%)
• Gaps: 66/294 - (22%)

  Fly   683 VIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTVE---GPQFCQGIDCQELIQGSLEK 744
            ||...|..|.:..|..::.|:...|.:..:  :.:|.|:.::   |..||.|.|.:.|.:.  :|
Mouse    47 VITLNRPKFLNALSLNMIRQIYPQLKTWEQ--DPDTFLIIIKGAGGKAFCAGGDIKALSEA--KK 107

  Fly   745 RKDSASQLAVALKCYL-RTLATFPKPLVAGIVGSQINLGVMQLPFADYVVASDDCSFETNYAKLG 808
            .:.:.:|.....:..| ..:|:..||.||.|.|..:..||.......:.||::...|......:|
Mouse   108 ARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIG 172

  Fly   809 QLPE--------------GYAL-WHGHQRVSSEVH-----------SRLFLMGERLFATE----- 842
            ..|:              ||.| ..|::....:||           .:|.::.|.|.|.:
Mouse   173 LFPDVGGGYFLPRLQGKLGYFLALTGYRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAE 237

  Fly   843 ----LLES---------------NSFVDKI--CKARNVNEMALAKAKQISTSSA-EMYRTLKKLN 885
                :|||               ...:|||  |.:.|..|..:...:|..:..| |..:.:.|::
Mouse   238 DVAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQMKVINKMS 302

  Fly   886 HSAVNVTKFPRLDEELK-----VIGEQWVTADCL 914
            .:::.:|....::...|     :|.|..:|..|:
Mouse   303 PTSLKITLRQLMEGSSKTLQEVLIMEYRITQACM 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628
		crotonase-like	673..870	CDD:119339	51/242 (21%)
Hibch	NP_666220.1	ECH_2	46..375	CDD:465024	61/294 (21%)