Protein Alignment HIPP1 and ech-4

DIOPT Version :10

• Sequence 1: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_001366707.1
• Gene: ech-4 / 174665
• WormBaseID: WBGene00001153
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 97/419 - (23%)
• Similarity: 153/419 - (36%)
• Gaps: 130/419 - (31%)

  Fly   548 ESAQ---SAAKRTPADSV-------FTKATA-NTSARKP-------RAS-DSWDYVYKQRASEES 593
            |.||   ...|..|.:.|       |.:||| :...::|       ||. |:|:.:..|...|..
 Worm    30 EKAQKNLKTLKEEPDNDVKLQLYGLFKQATAGDVQGKRPGMMDFVGRAKYDAWNTLKGQTQDEAR 94

  Fly   594 MIMRRRSNSSYSSNASVSRNSLDNRPGAANLSDDAGEGSDPSFKFVKPVSKSSQRGGEDTSSHTL 658
            ....:......|..||.                 |.|.:.||.:           |.|:....::
 Worm    95 ANYAKLVGGLISEEASA-----------------APEPTGPSIE-----------GLENVDGLSV 131

  Fly   659 ANDMKANNGSELVCLHKVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNTVLLTV 723
            ..:.|...    :.|::..|...|.:...:|     ..|.|....||..:|:        .::|.
 Worm   132 TREGKVFK----IALNRPKKFNALTLEMYQG-----IQKALEVSNNDKSTSI--------TVITA 179

  Fly   724 EGPQFCQGIDC---QELIQGSLEKRKDSASQLAVALKCYLRTLATFPKPLVAGIVGSQINLGVMQ 785
            .|..:|.|.|.   :....|:.|:..|.|:...|.:|.|:.......|||:|.|.|..:.:.|..
 Worm   180 NGSYYCAGNDLTNFKAAAGGTKEQIADMANTAKVIMKDYVNAYINHEKPLIALINGPAVGIAVTV 244

  Fly   786 LPFADYVVASDDCSFETNYAKLGQLPEGYALWHGHQRVSSEVHSRLFLMGERLFATELLESNSFV 850
            |...|||:|:|..||.|.:|.|||.|||         |||  ::...:||. |.|:|:|
 Worm   245 LGMFDYVIATDKASFHTPFAPLGQSPEG---------VSS--YTFPLIMGS-LRASEML------ 291

  Fly   851 DKICKARNVNEMALAKAKQISTSSAEMYRTLKKL-------NHSAVNVTKFPRLDEE-------- 900
             .:|             |:||..:|:.|..:.::       :|:...|..|.:|..|
 Worm   292 -LVC-------------KKISAQTAKDYGLVNEVVPDAEFQSHAQKTVEAFSQLPPETLRINKKL 342

  Fly   901 ---------LKV-------IGEQWVTADC 913
                     |:|       |.|:|.:.:|
 Worm   343 LRSLHKEKLLEVNNIEADQICERWQSKEC 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628	13/50 (26%)
		crotonase-like	673..870	CDD:119339	55/199 (28%)
ech-4	NP_001366707.1	ACBP	25..109	CDD:238248	18/78 (23%)
		CaiD	129..381	CDD:440647	71/292 (24%)