DRSC/TRiP Functional Genomics Resources

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Protein Alignment tzn and LACTB2

DIOPT Version :9

Sequence 1:NP_730568.1 Gene:tzn / 40299 FlyBaseID:FBgn0037024 Length:348 Species:Drosophila melanogaster
Sequence 2:NP_057111.1 Gene:LACTB2 / 51110 HGNCID:18512 Length:288 Species:Homo sapiens


Alignment Length:338 Identity:72/338 - (21%)
Similarity:119/338 - (35%) Gaps:132/338 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 MHSTLEDVQ-LEGMEIKIL------PALQDNYMYLI--------VDTKTREAAVVDPVEPELVIK 127
            |.:.|:.|: |....:::|      ..||....||:        :||.       :|..||.:  
Human     1 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTG-------EPAIPEYI-- 56

  Fly   128 TVQEQQLT-----LSKVLTTHHHWDHAGGNEKLLKLWEKELDVYGGDDRIGALNKKVQQDDTFTI 187
            :..:|.||     :.:::.||.|.||:||                    ||.:.|.:..|.|:.|
Human    57 SCLKQALTEFNTAIQEIVVTHWHRDHSGG--------------------IGDICKSINNDTTYCI 101

  Fly   188 -------------------------------GGLHVKCLSTPCHTTGHICYHITAQQGSGEGAVF 221
                                           .|..::.|.||.||..|:...:     ..|.|:|
Human   102 KKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLL-----EEENAIF 161

  Fly   222 TGDTLFQGGCGRFFEGTPEEMYEALCTKLSALPDATK-----VFCGHEYTLQNMSFARHVEPDNE 281
            :||.:..       |||  .::|.|...:::|.:..|     ::.||...:.|.         ..
Human   162 SGDCILG-------EGT--TVFEDLYDYMNSLKELLKIKADIIYPGHGPVIHNA---------EA 208

  Fly   282 VIQQRIEWAKHRRASQDPTVPSTIGE--EKSW-----------NPFMRVHEATVQKHAGGATDPV 333
            .|||.|   .||.. ::..:.:...|  |||:           |....:||  :.||     :.:
Human   209 KIQQYI---SHRNI-REQQILTLFRENFEKSFTVMELVKIIYKNTPENLHE--MAKH-----NLL 262

  Fly   334 VTMGKLRKEKDTF 346
            :.:.||.||...|
Human   263 LHLKKLEKEGKIF 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tznNP_730568.1 PLN02469 90..347 CDD:178088 68/325 (21%)
hydroxyacylglutathione_hydrolase_MBL-fold 93..263 CDD:293809 45/224 (20%)
HAGH_C 264..344 CDD:292741 20/92 (22%)
LACTB2NP_057111.1 LACTB2-like_MBL-fold 14..203 CDD:293808 47/231 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0491
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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