DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tzn and SPAC824.07

DIOPT Version :9

Sequence 1:	NP_730568.1	Gene:	tzn / 40299	FlyBaseID:	FBgn0037024	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_593446.1	Gene:	SPAC824.07 / 2542447	PomBaseID:	SPAC824.07	Length:	256	Species:	Schizosaccharomyces pombe

Alignment Length:	249	Identity:	106/249 - (42%)
Similarity:	153/249 - (61%)	Gaps:	14/249 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 DNYMYLIVDTKTREAAVVDPVEPELVIKTVQE----QQLTLSKVLTTHHHWDHAGGNEKLLKLWE 160
            :||.||:...||:..|:|||.|||.||..::|    :::.|..:||||||:|||||||.:|..:
pombe    16 NNYAYLLTCDKTKITAIVDPAEPESVIPVIKEKTAKKEIDLQYILTTHHHYDHAGGNEDILSYF- 79

  Fly   161 KELDVYGGDDRIGALNKKVQQDDTFTIGGLHVKCLSTPCHTTGHICYHITAQQGSGEGAVFTGDT 225
            ..|.||||.:..| :....:..:.|.:|.:.|:.|.|||||...|||::::   ..:.|||||||
pombe    80 PSLKVYGGKNASG-VTYTPKDKEIFKVGEVQVEALHTPCHTQDSICYYVSS---PSKRAVFTGDT 140

  Fly   226 LFQGGCGRFFEGTPEEMYEALCTKLSALPDATKVFCGHEYTLQNMSFARHVEPDNEVIQQRIEWA 290
            ||..||||||||..::|..||...|:||||.|..:.|||||..|..|:..:....| :.:.:::.
pombe   141 LFTSGCGRFFEGDAKQMDYALNHVLAALPDDTVTYPGHEYTKSNAKFSSTIFSTPE-LTKLVDFC 204

  Fly   291 KHRRASQDPTVPSTIGEEKSWNPFMRVHEATVQKHAGGATDPVVTMGKLRKEKD 344
            |:..::   |...|||:||.:||||.:...:||| |.|::||:..|.|||..|:
pombe   205 KNHEST---TGHFTIGDEKKFNPFMCLGLESVQK-AVGSSDPITVMKKLRDMKN 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tzn	NP_730568.1	PLN02469	90..347	CDD:178088	106/249 (43%)
		hydroxyacylglutathione_hydrolase_MBL-fold	93..263	CDD:293809	75/166 (45%)
		HAGH_C	264..344	CDD:292741	28/79 (35%)
SPAC824.07	NP_593446.1	PLN02469	16..254	CDD:178088	105/247 (43%)
		hydroxyacylglutathione_hydrolase_MBL-fold	17..178	CDD:293809	75/165 (45%)
		HAGH_C	179..254	CDD:292741	28/79 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	143	1.000	Domainoid score	I1168
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I1043
OMA	1	1.010	-	-		QHG54141
OrthoFinder	1	1.000	-	-		FOG0001231
OrthoInspector	1	1.000	-	-		otm47380
orthoMCL	1	0.900	-	-		OOG6_101019
Panther	1	1.100	-	-	LDO	PTHR11935
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R494
SonicParanoid	1	1.000	-	-		X446
TreeFam	1	0.960	-	-
	13	12.860