DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tzn and Hagh

DIOPT Version :9

Sequence 1:	NP_730568.1	Gene:	tzn / 40299	FlyBaseID:	FBgn0037024	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_203500.2	Gene:	Hagh / 24439	RGDID:	2779	Length:	309	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	164/263 - (62%)
Similarity:	202/263 - (76%)	Gaps:	2/263 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VQLEGMEIKILPALQDNYMYLIVDTKTREAAVVDPVEPELVIKTVQEQQLTLSKVLTTHHHWDHA 149
            ||.:.|:|::||||.|||||||:|..|:||||||||:|:.||:||::.::.|:.|||||||||||
  Rat    45 VQQDMMKIELLPALTDNYMYLIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHA 109

  Fly   150 GGNEKLLKLWEKELDVYGGDDRIGALNKKVQQDDTFTIGGLHVKCLSTPCHTTGHICYHITAQQG 214
            ||||||:|| |..|.|||||||||||..||....|..:|.|.||||||||||:|||||.::....
  Rat   110 GGNEKLVKL-EPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGS 173

  Fly   215 SGEGAVFTGDTLFQGGCGRFFEGTPEEMYEALCTKLSALPDATKVFCGHEYTLQNMSFARHVEPD 279
            |...|||||||||..|||:|:|||.:|||:||...|..||..|||:||||||:.|:.|||||||.
  Rat   174 SEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVNNLKFARHVEPG 238

  Fly   280 NEVIQQRIEWAKHRRASQDPTVPSTIGEEKSWNPFMRVHEATVQKHAGGATDPVVTMGKLRKEKD 344
            |..:|:::.|||.:.|..:||||||:.||.::||||||.|.|||:|| |.||||.||..:|:|||
  Rat   239 NTAVQEKLAWAKEKNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHA-GETDPVTTMRAIRREKD 302

  Fly   345 TFK 347
            .||
  Rat   303 QFK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tzn	NP_730568.1	PLN02469	90..347	CDD:178088	160/256 (63%)
		hydroxyacylglutathione_hydrolase_MBL-fold	93..263	CDD:293809	108/169 (64%)
		HAGH_C	264..344	CDD:292741	46/79 (58%)
Hagh	NP_203500.2	PLN02469	50..305	CDD:178088	160/256 (63%)
		hydroxyacylglutathione_hydrolase_MBL-fold	55..222	CDD:293809	108/167 (65%)
		HAGH_C	223..303	CDD:292741	47/80 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352072
Domainoid	1	1.000	214	1.000	Domainoid score	I2647
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3890
Inparanoid	1	1.050	341	1.000	Inparanoid score	I2282
OMA	1	1.010	-	-		QHG54141
OrthoDB	1	1.010	-	-		D506792at33208
OrthoFinder	1	1.000	-	-		FOG0001231
OrthoInspector	1	1.000	-	-		oto98332
orthoMCL	1	0.900	-	-		OOG6_101019
Panther	1	1.100	-	-	LDO	PTHR11935
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X446
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770