Protein Alignment Six4 and six4a

DIOPT Version :10

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_571793.2
• Gene: six4a / 65233
• ZFINID: ZDB-GENE-010201-2
• Length: 593
• Species: Danio rerio
• Alignment Length: 271
• Identity: 135/271 - (49%)
• Similarity: 168/271 - (61%)
• Gaps: 50/271 - (18%)

  Fly   163 AHNMSAVSSFPIDAKMLQFSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRARAM 227
            ||:..||:     |..|.||.:|:.|:||||||.|::::|..||.|||.|:..:.|||:|||:|:
Zfish    69 AHSSPAVT-----ATSLAFSPEQVACVCEALQQGGNVDRLARFLWSLPQSDLLRGNESILRAQAL 128

  Fly   228 VAYNLGQFHELYNLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKT 292
            ||::..::.|||::||:|.||...|..||:||:||.|.||||.||||||||||||||:|:|||:|
Zfish   129 VAFHQARYQELYSILESHSFSPSCHSALQDLWYKARYTEAEKARGRPLGAVDKYRLRRKFPLPRT 193

  Fly   293 IWDGEETVYCFKEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQQ- 356
            |||||||||||||:|||||||.|..||||:|.||:.|||.|||:||||||||||||||||.|.:
Zfish   194 IWDGEETVYCFKERSRNALKDLYKQNRYPSPAEKRNLAKITGLSLTQVSNWFKNRRQRDRNPSET 258

  Fly   357 -----------------------RPDIMSVLPVGQLDGNGFP------------------RMFNA 380
                                   .|..||....|.:.....|                  |...:
Zfish   259 QSKSESDGNHSTEDESSKGQESLSPCPMSTCADGPVSNTALPLCSGSLDAGVIVQQVADSRTSIS 323

  Fly   381 PSYYPETIFNG 391
            |   |..||||
Zfish   324 P---PSVIFNG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:465293	63/108 (58%)
		homeodomain	301..355	CDD:238039	42/53 (79%)
six4a	NP_571793.2	SIX1_SD	82..191	CDD:465293	63/108 (58%)
		homeodomain	202..256	CDD:238039	42/53 (79%)