Protein Alignment Six4 and six2b

DIOPT Version :10

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001122206.1
• Gene: six2b / 566454
• ZFINID: ZDB-GENE-080723-23
• Length: 285
• Species: Danio rerio
• Alignment Length: 177
• Identity: 111/177 - (62%)
• Similarity: 135/177 - (76%)
• Gaps: 0/177 - (0%)

  Fly   181 FSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRARAMVAYNLGQFHELYNLLETH 245
            |:.:|:.|:||.|||.|.||:|..||.|||..|....|||||:|:|:||::.|.|.|||.:||:|
Zfish     9 FTQEQVACVCEVLQQGGSIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKVLESH 73

  Fly   246 CFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKTIWDGEETVYCFKEKSRNA 310
            .||...|..||.||.||||.||||:||||||||.|||:|:|:|||::|||||||.||||||||..
Zfish    74 QFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRCV 138

  Fly   311 LKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQQR 357
            ||:.|..|.||:|.||:.||:.||||.|||||||||||||||..:.:
Zfish   139 LKEWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:465293	64/108 (59%)
		homeodomain	301..355	CDD:238039	38/53 (72%)
six2b	NP_001122206.1	SIX1_SD	9..118	CDD:465293	64/108 (59%)
		homeodomain	129..180	CDD:238039	36/50 (72%)