Protein Alignment Six4 and Six2

DIOPT Version :10

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: XP_038968544.1
• Gene: Six2 / 366542
• RGDID: 1310792
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 177
• Identity: 110/177 - (62%)
• Similarity: 137/177 - (77%)
• Gaps: 0/177 - (0%)

  Fly   181 FSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRARAMVAYNLGQFHELYNLLETH 245
            |:.:|:.|:||.|||.|:||:|..||.|||..|....|||||:|:|:||::.|.|.|||.:||:|
  Rat     9 FTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESH 73

  Fly   246 CFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKTIWDGEETVYCFKEKSRNA 310
            .||...|..||.||.||||.||||:||||||||.|||:|:|:|||::|||||||.||||||||:.
  Rat    74 QFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSV 138

  Fly   311 LKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQQR 357
            |::.|..|.||:|.||:.||:.||||.|||||||||||||||..:.:
  Rat   139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:465293	64/108 (59%)
		homeodomain	301..355	CDD:238039	37/53 (70%)
Six2	XP_038968544.1	SIX1_SD	9..118	CDD:465293	64/108 (59%)
		homeodomain	129..180	CDD:238039	35/50 (70%)