Protein Alignment Six4 and Six6

DIOPT Version :10

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001101502.1
• Gene: Six6 / 314221
• RGDID: 1310497
• Length: 246
• Species: Rattus norvegicus
• Alignment Length: 217
• Identity: 112/217 - (51%)
• Similarity: 151/217 - (69%)
• Gaps: 14/217 - (6%)

  Fly   178 MLQFSTDQIQCMCEALQQKGDIEKLTTFLCSLPPS----EFFKTNESVLRARAMVAYNLGQFHEL 238
            :|.||..|:..:||.|::.||:|:|..||.|||.:    |....|||||||||:||::.|.:.||
  Rat     6 ILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIVAFHGGNYREL 70

  Fly   239 YNLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKTIWDGEETVYCF 303
            |::||.|.|:.:.|..||.||.:|||:||||:||||||.|||||:|||:|||:||||||:..:||
  Rat    71 YHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCF 135

  Fly   304 KEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTP------QQRPDIMS 362
            ||::|:.|::.||.:.||.|.:|:.||:.||||.|||.|||||||||||..      ||:  ::|
  Rat   136 KERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQ--VLS 198

  Fly   363 VLP--VGQLDGNGFPRMFNAPS 382
            ..|  |.:.:|.|.|.:....|
  Rat   199 QGPGRVLRSEGEGTPEVLGVAS 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:465293	62/112 (55%)
		homeodomain	301..355	CDD:238039	32/59 (54%)
Six6	NP_001101502.1	SIX1_SD	9..122	CDD:465293	62/112 (55%)
		homeodomain	130..178	CDD:238039	24/47 (51%)