Protein Alignment Six4 and Six4

DIOPT Version :10

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001401848.1
• Gene: Six4 / 299138
• RGDID: 1306726
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 136/277 - (49%)
• Similarity: 170/277 - (61%)
• Gaps: 34/277 - (12%)

  Fly    96 SPPPTASTTPTHYPSLNSIIFENGSSGNLGDLNGNTKTDLCAGLQRSGGGLGGNAGSGGHLISNL 160
            |||     .|..:|      .|.|.:.            ..:.:.|..|.....|.....|.|.|
  Rat    44 SPP-----APAPFP------LEPGDAA------------AASRVSREEGAAAAGAADQVQLHSEL 85

  Fly   161 TAAHNMSAVSSFPIDAKMLQFSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRAR 225
            ...|..:|.:..|     |.||.|.:.|:||||||.|::::|..||.|||.|:..:.|||:|:||
  Rat    86 LGRHQHAATAQPP-----LAFSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNESLLKAR 145

  Fly   226 AMVAYNLGQFHELYNLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLP 290
            |:||::.|.:.|||::||:|.|....|..||.||:||.|.|||:.||||||||||||||:|:|||
  Rat   146 ALVAFHQGIYPELYSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLP 210

  Fly   291 KTIWDGEETVYCFKEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQ 355
            :|||||||||||||||||||||:.|..||||:|.||:.|||.|||:||||||||||||||||.|.
  Rat   211 RTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPS 275

  Fly   356 QRPDIMSVLPVGQLDGN 372
            :...      ..:.|||
  Rat   276 ETQS------KSESDGN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:465293	62/108 (57%)
		homeodomain	301..355	CDD:238039	42/53 (79%)
Six4	NP_001401848.1	SIX1_SD	101..210	CDD:465293	47/108 (44%)
		homeodomain	221..275	CDD:238039	44/53 (83%)