Protein Alignment Six4 and Six4

DIOPT Version :9

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: XP_006240269.1
• Gene: Six4 / 299138
• RGDID: 1306726
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 136/277 - (49%)
• Similarity: 170/277 - (61%)
• Gaps: 34/277 - (12%)

  Fly    96 SPPPTASTTPTHYPSLNSIIFENGSSGNLGDLNGNTKTDLCAGLQRSGGGLGGNAGSGGHLISNL 160
            |||     .|..:|      .|.|.:.            ..:.:.|..|.....|.....|.|.|
  Rat    44 SPP-----APAPFP------LEPGDAA------------AASRVSREEGAAAAGAADQVQLHSEL 85

  Fly   161 TAAHNMSAVSSFPIDAKMLQFSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRAR 225
            ...|..:|.:..|     |.||.|.:.|:||||||.|::::|..||.|||.|:..:.|||:|:||
  Rat    86 LGRHQHAATAQPP-----LAFSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNESLLKAR 145

  Fly   226 AMVAYNLGQFHELYNLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLP 290
            |:||::.|.:.|||::||:|.|....|..||.||:||.|.|||:.||||||||||||||:|:|||
  Rat   146 ALVAFHQGIYPELYSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLP 210

  Fly   291 KTIWDGEETVYCFKEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQ 355
            :|||||||||||||||||||||:.|..||||:|.||:.|||.|||:||||||||||||||||.|.
  Rat   211 RTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPS 275

  Fly   356 QRPDIMSVLPVGQLDGN 372
            :...      ..:.|||
  Rat   276 ETQS------KSESDGN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:293483	62/108 (57%)
		homeodomain	301..355	CDD:238039	42/53 (79%)
Six4	XP_006240269.1	SIX1_SD	101..210	CDD:293483	47/108 (44%)
		homeodomain	221..275	CDD:238039	44/53 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352059
Domainoid	1	1.000	88	1.000	Domainoid score	I7773
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45655
orthoMCL	1	0.900	-	-		OOG6_109892
Panther	1	1.100	-	-	O	PTHR10390
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3257
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.740