Protein Alignment Six4 and Six3

DIOPT Version :9

• Sequence 1: NP_649256.1
• Gene: Six4 / 40297
• FlyBaseID: FBgn0027364
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: XP_017172856.1
• Gene: Six3 / 20473
• MGIID: 102764
• Length: 354
• Species: Mus musculus
• Alignment Length: 282
• Identity: 128/282 - (45%)
• Similarity: 174/282 - (61%)
• Gaps: 29/282 - (10%)

  Fly   118 NGSSGNLGDLNGNTKTDLCAGLQRSG----GGLGGNAGSGGHLISNLTAAHNMSAVSSFPIDAKM 178
            :|:||..|...|.      .|..|:|    ||.||.:|.||       :......:|.|.:..
Mouse    57 SGASGGGGGAGGG------GGGNRAGGGGAGGAGGGSGGGG-------SRAPPEELSMFQLPT-- 106

  Fly   179 LQFSTDQIQCMCEALQQKGDIEKLTTFLCSLPPS----EFFKTNESVLRARAMVAYNLGQFHELY 239
            |.||.:|:..:||.|::.||||:|..||.|||.:    |....:||:|||||:||::.|.|.:||
Mouse   107 LNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLY 171

  Fly   240 NLLETHCFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKTIWDGEETVYCFK 304
            ::||.|.|:.:.|..||.:|.:|||:||||:||||||.|||||:|||:|||:||||||:..:|||
Mouse   172 HILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFK 236

  Fly   305 EKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDR--TPQQRPDIMSVLPVG 367
            |::|:.|::.||.:.||.|.:|:.||:.||||.|||.|||||||||||  ..:.|....::.|.|
Mouse   237 ERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSG 301

  Fly   368 --QLDGNGFPRMFNAPSYYPET 387
              .|...|.|...:|.|  |.|
Mouse   302 MRSLAEPGCPTHGSAES--PST 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Six4	NP_649256.1	SIX1_SD	181..290	CDD:293483	60/112 (54%)
		homeodomain	301..355	CDD:238039	32/55 (58%)
Six3	XP_017172856.1	SIX1_SD	109..222	CDD:374862	60/112 (54%)
		homeodomain	230..278	CDD:238039	24/47 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810