DRSC/TRiP Functional Genomics Resources

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Protein Alignment Six4 and Six2

DIOPT Version :9

Sequence 1:NP_649256.1 Gene:Six4 / 40297 FlyBaseID:FBgn0027364 Length:392 Species:Drosophila melanogaster
Sequence 2:XP_006523994.1 Gene:Six2 / 20472 MGIID:102778 Length:298 Species:Mus musculus


Alignment Length:177 Identity:110/177 - (62%)
Similarity:137/177 - (77%) Gaps:0/177 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 FSTDQIQCMCEALQQKGDIEKLTTFLCSLPPSEFFKTNESVLRARAMVAYNLGQFHELYNLLETH 245
            |:.:|:.|:||.|||.|:||:|..||.|||..|....|||||:|:|:||::.|.|.|||.:||:|
Mouse     9 FTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESH 73

  Fly   246 CFSIKYHVDLQNLWFKAHYKEAEKVRGRPLGAVDKYRLRKKYPLPKTIWDGEETVYCFKEKSRNA 310
            .||...|..||.||.||||.||||:||||||||.|||:|:|:|||::|||||||.||||||||:.
Mouse    74 QFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSV 138

  Fly   311 LKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNRRQRDRTPQQR 357
            |::.|..|.||:|.||:.||:.||||.|||||||||||||||..:.:
Mouse   139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Six4NP_649256.1 SIX1_SD 181..290 CDD:293483 64/108 (59%)
homeodomain 301..355 CDD:238039 37/53 (70%)
Six2XP_006523994.1 SIX1_SD 9..118 CDD:407119 64/108 (59%)
homeodomain 129..180 CDD:238039 35/50 (70%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0775
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001063
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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