Protein Alignment CG11399 and Pcif1

DIOPT Version :9

• Sequence 1: NP_649254.2
• Gene: CG11399 / 40295
• FlyBaseID: FBgn0037021
• Length: 920
• Species: Drosophila melanogaster
• Sequence 2: XP_038961470.1
• Gene: Pcif1 / 362269
• RGDID: 1310800
• Length: 721
• Species: Rattus norvegicus
• Alignment Length: 709
• Identity: 312/709 - (44%)
• Similarity: 439/709 - (61%)
• Gaps: 56/709 - (7%)

  Fly   100 SPSTPTKTHAPSPLESMGHTPQGPPTLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGE 164
            ||.......:.||..|..:.|..|.   |....::|..|||:.||.|.||:||:||||:|:.|.:
  Rat    25 SPREEASLLSHSPGTSNQNQPCSPK---PVRLVQDLPEELVHAGWEKCWSRRESRPYYFNRFTNQ 86

  Fly   165 SLWEMPGTRPFDPLTDPLGICHAGGP-------TPIIPNMHQQQQHQHHHLK----RRPSDDMHI 218
            ||||||.....|.|:||||:.....|       ||.:.|..:::|.......    ::|..::.:
  Rat    87 SLWEMPVLGQHDVLSDPLGLNATPLPQDSTLVETPPVENKPRKRQLSEEQPSGNGVKKPKIEIPV 151

  Fly   219 HPNQHHMGGGPPM---------------KKFVLAGP----WDLEVCTNAVIVERPPTLLPQPHPE 264
            .|....:...|.:               |:..|..|    |||::.|||||..|.|:.:..||||
  Rat   152 TPTSQSVPSSPSIPGTPILKIWGASTEDKQAALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPE 216

  Fly   265 VEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYR 329
            ||.||:...:||.:.|.:||.:||.|:.||:|||||::||||:|.||||||||:|.|.:|.||:|
  Rat   217 VELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFR 281

  Fly   330 EIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGAS 394
            |||:||||::.:.||..:|::.|.:|||||:::||||||..:|:|||||||||||.|||:...||
  Rat   282 EIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSAS 346

  Fly   395 YEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPP 459
            .||:.|||.||:|||.||:....|.|||.:|.||||:|.::.::|||:|..:|||:.|||.....
  Rat   347 KEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEEVEAS 411

  Fly   460 P-PPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYR 523
            . .|.|  |:|||::.||.:|.||::|...:...:.|:|....:.      ::.:|..||..|||
  Rat   412 ELEPRL--VYCYPVRLAVSAPPMPSVEMHMENSVVCIRYKGEMVK------VSRSYFSKLWLLYR 468

  Fly   524 HNCFDDKKFDLFIGRVWCLLKRYQTFLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFAS 588
            ::|.||..|:.|:.||||||:|||...|..|   .|....|.:|||.|||.|||.||||||||||
  Rat   469 YSCVDDSAFERFLPRVWCLLRRYQMMFGVGL---YEGTGLQGSLPVHVFEALHRLFGVSFECFAS 530

  Fly   589 PFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPL 653
            |.|.|||||||||.|||.|||||||.|||.|:||||:.|||.||||::|.:.|.:|||..:.|||
  Rat   531 PLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPL 595

  Fly   654 SFIVFLPEWK-----SISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWL 713
            |||||:|||:     ::::::.|.:||..:|:....||||.|.||:.:|.::..|.:..|.|::|
  Rat   596 SFIVFIPEWREPPTPALTRMEQSRFKRHQLVLSAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFL 660

  Fly   714 QNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGV-----TSSQQSPSTPP 767
            ||..|:|:|||...|::.|..|:: |..|....::::::::..     :..:|.||..|
  Rat   661 QNDPGFAKWGPTPERLQELTAAYK-QSGRSHGSSSSSSSSSSEAKDRDSGREQGPSREP 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11399	NP_649254.2	WW	143..170	CDD:238122	17/26 (65%)
		PCIF1_WW	524..685	CDD:289041	93/165 (56%)
Pcif1	XP_038961470.1	WW	64..94	CDD:238122	19/29 (66%)
		PCIF1_WW	462..632	CDD:403450	98/172 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338555
Domainoid	1	1.000	293	1.000	Domainoid score	I1454
eggNOG	1	0.900	-	-		E1_28P6D
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11134
Inparanoid	1	1.050	593	1.000	Inparanoid score	I935
OMA	1	1.010	-	-		QHG52676
OrthoDB	1	1.010	-	-		D114954at33208
OrthoFinder	1	1.000	-	-		FOG0007279
OrthoInspector	1	1.000	-	-		oto96686
orthoMCL	1	0.900	-	-		OOG6_106120
Panther	1	1.100	-	-	LDO	PTHR21727
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5383
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770