Protein Alignment Pcif1 and Pcif1

DIOPT Version :10

• Sequence 1: NP_649254.2
• Gene: Pcif1 / 40295
• FlyBaseID: FBgn0037021
• Length: 920
• Species: Drosophila melanogaster
• Sequence 2: NP_001361055.1
• Gene: Pcif1 / 228866
• MGIID: 2443858
• Length: 723
• Species: Mus musculus
• Alignment Length: 753
• Identity: 318/753 - (42%)
• Similarity: 449/753 - (59%)
• Gaps: 93/753 - (12%)

  Fly    60 ASASNNMSPSPTAGAPTVTGPILPDNLGVGAGSSPVASCSSPSTPTKTHAPSPLESMGHTPQGPP 124
            |..:|....||..||     .:|..:.|..:.|.|   ||          |.|:..:
Mouse    16 AEMANENHGSPREGA-----SLLSHSPGTSSQSQP---CS----------PKPVRLV-------- 54

  Fly   125 TLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGESLWEMPGTRPFDPLTDPLGICHAGG 189
                    ::|..|||:.||.|.||:||:||||:|:.|.:||||||.....|.|:||||:.....
Mouse    55 --------QDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPL 111

  Fly   190 P-------TPIIPNMHQQQQHQHHHLK----RRPSDDMHIHPNQHHMGGGPPM------------ 231
            |       ||.:.|..:::|.......    ::|..::.:.|....:...|.:
Mouse   112 PQDSSLVETPPVENKSRKRQLSEEQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPTLKIWGSS 176

  Fly   232 ---KKFVLAGP----WDLEVCTNAVIVERPPTLLPQPHPEVEALRAAFTMKLLKTYEDLCMRREN 289
               |:..|..|    |||::.|||||..|.|:.:..|||:||.||:...:||.:.|.:||.:||.
Mouse   177 TEDKQAALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPDVELLRSQLILKLRQHYRELCQQREG 241

  Fly   290 IKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYREIMSDIPIKIVKPKFTGDARKQLSR 354
            |:.||:|||||::||||:|.||||||||:|.|.:|.||:||||:||||::.:.||..:|::.|.:
Mouse   242 IEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFK 306

  Fly   355 YAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGASYEDFQDRLAHLKRQCEPHLVETVKS 419
            |||||:::||||||..:|:|||||||||||.|||:...||.||:.|||.||:|||.||:....|.
Mouse   307 YAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKD 371

  Fly   420 SVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPPP-PPHLKKVWCYPIQFAVPSPRMPT 483
            |||.:|.||||:|.::.::|||:|..:|||:.|||...... .|.|  |:|||::.||.:|.||:
Mouse   372 SVEGICSKIYHISLEYVKRIREKHLAVLKENNIPEEVEASELEPRL--VYCYPVRLAVSAPPMPS 434

  Fly   484 IEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYRHNCFDDKKFDLFIGRVWCLLKRYQT 548
            :|...:...:.|:|....:.      ::.:|..||..|||::|.||..|:.|:.||||||:|||.
Mouse   435 VEMHVENSVVCIRYKGEMVK------VSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQM 493

  Fly   549 FLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFASPFNSYFRQYCSAFADTDAYFGSRGP 613
            ..|..|   .|....|.:|||.|||.|||.|||||||||||.|.|||||||||.|||.|||||||
Mouse   494 MFGVGL---YEGTGLQGSLPVHVFETLHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGP 555

  Fly   614 FLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPLSFIVFLPEWK-----SISKLDDSMY 673
            .|||.|:||||:.|||.||||::|.:.|.:|||..:.||||||||:|||:     ::::::.|.:
Mouse   556 CLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSAEPLSFIVFIPEWREPPTPALTRMEQSRF 620

  Fly   674 KRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWLQNSAGYARWGPNEIRVEALREAFRP 738
            ||..:|:....||||.|.||:.:|.::..|.:..|.|::|||..|:|:|||...|::.|..|:
Mouse   621 KRHQLVLPAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNGPGFAKWGPTPERLQELTAAY-- 683

  Fly   739 QRDRERERAAAAAAAAGVTSS---------QQSPSTPP 767
             :...|...:::::::..:||         :|.||..|
Mouse   684 -KQSGRSHGSSSSSSSSSSSSEAKDRDSGREQGPSREP 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcif1	NP_649254.2	WW	143..170	CDD:459800	17/26 (65%)
		PCIF1_WW	517..685	CDD:463502	98/172 (57%)
Pcif1	NP_001361055.1	WW	64..94	CDD:238122	3/29 (10%)
		PCIF1_WW	462..632	CDD:463502	97/174 (56%)