Protein Alignment Pcif1 and Pcif1

DIOPT Version :10

• Sequence 1: NP_649254.2
• Gene: Pcif1 / 40295
• FlyBaseID: FBgn0037021
• Length: 920
• Species: Drosophila melanogaster
• Sequence 2: XP_061509046.1
• Gene: Pcif1 / 1280736
• VectorBaseID: AGAMI1_012817
• Length: 794
• Species: Anopheles gambiae
• Alignment Length: 838
• Identity: 471/838 - (56%)
• Similarity: 557/838 - (66%)
• Gaps: 116/838 - (13%)

  Fly    50 AAQSAWDQLTASASNN----------------------MSPSPTAGAP-TVTGPILPDNLGVGAG 91
            ||.|||||||..:...                      .||...|.:| |::.|:|
Mosquito    16 AAPSAWDQLTNPSLAEQQHPQHQQQQVPPLHQHQHHPAQSPQMQASSPTTISAPLL--------- 71

  Fly    92 SSPVASCSSPSTPTKTHAPSPLESMGHTPQGPPTLGPG-GYGEELTAELVNQGWRKFWSKRENRP 155
                       |||||..|    .:.|||.|.....|| .:.|||..||..|||||||||||.||
Mosquito    72 -----------TPTKTTPP----DVAHTPSGAAPGAPGANFNEELAPELTQQGWRKFWSKREGRP 121

  Fly   156 YYWNKVTGESLWEMP----GTRPFDPLTDPLGICHA---GGPTPI------IPNMHQQQQHQHHH 207
            |:|||:|||||||.|    |...|||||||||||..   .||.|:      ..|.|....:.||.
Mosquito   122 YFWNKLTGESLWEPPQLNRGPPQFDPLTDPLGICSTSPLNGPLPMHNSTGYNNNSHPSPHNHHHT 186

  Fly   208 LKRRPSDD-------------MHIHPNQHHMGGGPPMKKFVLAGPWDLEVCTNAVIVERPPTLLP 259
            ||||.|:|             .|:.|....:||.||:||:||.|||||||.||.:|.||.||..|
Mosquito   187 LKRRASEDAAQQQPQQQQHHSAHLPPGAGSVGGPPPLKKYVLPGPWDLEVPTNVLIYERLPTTFP 251

  Fly   260 QPHPEVEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEIS 324
            ||:|||||||.:.|::|.|||||||.:||:|..|:|||.||||||::||.|.||||||.|.||||
Mosquito   252 QPYPEVEALRGSLTLRLAKTYEDLCNKRESIAPPKDSFQRWLMERRIIDQGIDPLLPSQCTPEIS 316

  Fly   325 SSMYREIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRR 389
            ..|||||:.||||||||||||||||||||||.:|||:|:|.|.|..||||:||||.::.::||||
Mosquito   317 PQMYREILRDIPIKIVKPKFTGDARKQLSRYCDAAKKIVERRGASEESKKIVKWNADEAYEWLRR 381

  Fly   390 TVGASYEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPE 454
            |||||||||||||.||:||||||::.||:.|||.||.|:||||..|||.|||||:|:||||||||
Mosquito   382 TVGASYEDFQDRLTHLQRQCEPHIIATVRVSVEQLCAKLYHLSMQHARNIRERHAQILKEHGIPE 446

  Fly   455 PTPPPPPPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYT-PATINQPDAQYINLTYLQKL 518
            .:.|..||..:||||||:|||:||||||.|:|..|||||:|||| .|.:..||...:|:::||||
Mosquito   447 LSAPLQPPVTRKVWCYPVQFALPSPRMPQIDYSNDRDHMVIKYTNTAVMAAPDTHVVNISHLQKL 511

  Fly   519 EQLYRHNCFDDKKFDLFIGRVWCLLKRYQTFLGNALN-SSQEAELTQAALPVPVFECLHRQFGVS 582
            |||||:|||||||||.||||.:|:||||.|||||..| :.||.||||||||..||||||..|.|:
Mosquito   512 EQLYRYNCFDDKKFDFFIGRAYCMLKRYATFLGNNANPNQQEPELTQAALPAVVFECLHHHFNVT 576

  Fly   583 FECFASPFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLT 647
            |||||||.|.|||||||||.|||::|||||.||||||||||||||||:|||||:|||.|||:|||
Mosquito   577 FECFASPLNCYFRQYCSAFGDTDSFFGSRGSFLDFKPVSGSFQVNPPYCEELIDASLQHIDRLLT 641

  Fly   648 DTMEPLSFIVFLPEWKS-----ISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQG 707
            |::|||||||||.|||.     :||::||.|||:.:||:||.||||||.||.:.||:|..|.:.|
Mosquito   642 DSVEPLSFIVFLQEWKDPPLKCLSKIEDSPYKRKQVVVMGMEHEYRHGLQHCIPKSEVNFKSIVG 706

  Fly   708 TQVVWLQNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGVTSSQQSPSTPPSAAST 772
            |.||||||:||||||.|.|.||:||.|||||.|:|:|::|.                    |.||
Mosquito   707 TMVVWLQNAAGYARWAPTEARVDALLEAFRPGRERDRDKAI--------------------ATST 751

  Fly   773 APTTNSCTISGVNSNSSSTATTTSTSSSPSLTTTSSSMSPLSPHTPTGNPPPQFPMTI 830
            .|...||               ::|:|||...|..:|.|.....:.||...|..|.|:
Mosquito   752 VPVQASC---------------SATASSPEPGTAGNSGSGAGDLSSTGPSKPSTPATV 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcif1	NP_649254.2	WW	143..170	CDD:459800	23/26 (88%)
		PCIF1_WW	517..685	CDD:463502	128/173 (74%)
Pcif1	XP_061509046.1	None