DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex14 and Pex14

DIOPT Version :9

Sequence 1:	NP_649253.1	Gene:	Pex14 / 40294	FlyBaseID:	FBgn0037020	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_742060.1	Gene:	Pex14 / 64460	RGDID:	68336	Length:	376	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	84/284 - (29%)
Similarity:	138/284 - (48%)	Gaps:	56/284 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GVDEQLPRESLITTAVSFLQNTKVRHTTLIQKQQFLRSKGLTAHEIQLACERAGVFTQDPNKPNP 91
            |.:..:|||.||.|||.||||::||.:.|..::.||:.||||..||.||.:::|..:.:|:...|
  Rat    18 GSENVVPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTDEEIDLAFQQSGTASDEPSPVGP 82

  Fly    92 -------NPNTVISIGSQLHALQPQPTVLGRIREIIHSAALFSGVVYAVYIFWKQYIAPYLF-GK 148
                   .|..:||        ||......|.|:....|.:.:|:.:..:..:|:|:.|.:. |:
  Rat    83 ATPVVPVQPPHLIS--------QPYSPGGSRWRDYGALAIILAGIAFGFHQLYKKYLLPLILGGR 139

  Fly   149 SKKKAVDEV---LDDIDKKVETRTNDLNKEILAVRDLITTQQREHAQQLNRE------------- 197
            ..:|.::.:   |.::...|......:...:.:|::|: .||::..|:|..|
  Rat   140 EDRKQLERMAASLSELSGSVAQTVTQVQTTLASVQELL-RQQQQKVQELAHELAAAKATTSTNWI 203

  Fly   198 -----FSNFRSDLDAIKGLLLNRKQFAGPVAPIAVPSIPAWQL------AGSPHHHHRHSGSD-- 249
                 .:..:|:::::|||||||:||  |.:|.| |.||:||:      ..||...:.||.||
  Rat   204 LESQNINELKSEINSLKGLLLNRRQF--PPSPSA-PKIPSWQIPVKSPSPSSPAAVNHHSSSDIS 265

  Fly   250 --DNEK-----GDDAGSGSGSSET 266
              .||.     |.|..|..||:.|
  Rat   266 PVSNESPSSSPGKDGHSPEGSTAT 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex14	NP_649253.1	Pex14_N	34..145	CDD:282540	39/117 (33%)
Pex14	NP_742060.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		1/4 (25%)
		Pex14_N	25..135	CDD:282540	38/116 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..93		6/29 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..376		13/37 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353297
Domainoid	1	1.000	66	1.000	Domainoid score	I9772
eggNOG	1	0.900	-	-		E1_KOG2629
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37936
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4812
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1033073at2759
OrthoFinder	1	1.000	-	-		FOG0004737
OrthoInspector	1	1.000	-	-		oto98635
orthoMCL	1	0.900	-	-		OOG6_105746
Panther	1	1.100	-	-	LDO	PTHR23058
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760