DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex14 and prx-14

DIOPT Version :9

Sequence 1:	NP_649253.1	Gene:	Pex14 / 40294	FlyBaseID:	FBgn0037020	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_502097.1	Gene:	prx-14 / 178026	WormBaseID:	WBGene00004199	Length:	258	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	62/224 - (27%)
Similarity:	103/224 - (45%)	Gaps:	34/224 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RESLITTAVSFLQNTKVRHTTLIQKQQFLRSKGLTAHEIQLACERAGVFTQDPNKPNPNPNT--V 96
            |..::..|..|:...||:.|...:::|||..||::..||..|  ||.:   .|.:......|  :
Worm    10 RPDMVEAARKFMLTPKVKETPFEEQRQFLLGKGVSEAEILEA--RASI---PPEQLRSQIGTENM 69

  Fly    97 ISIGSQLHALQPQPTVLGRIREII---HSAALFSGVVYAVYIFWKQYIAPYLFGKSKKKAVDEVL 158
            |.||.     .||..:..:...|:   .||.:...:.||.|.|.:.|:.|..|     ...|...
Worm    70 IPIGG-----HPQMMIAPKQNGIVSFAQSAVVLGSISYAGYRFVRSYVLPRFF-----DIPDPAT 124

  Fly   159 DDIDKKVETRTNDLNKEILAVRDLIT-------TQQREHAQQL----NR--EFSNFRSDLDAIKG 210
            ::| ::::::.:||...|..:.|.::       |||.|.::.|    ||  :.:...|.:..||.
Worm   125 EEI-RQLQSQVDDLQNSIKFIMDSVSQTTQQLATQQSEISRALYSVANRDADLNRVESGISTIKS 188

  Fly   211 LLLNRKQFAGPVAPIAVPSIPAWQLAGSP 239
            |||::..||..|.|....|||:||.:.:|
Worm   189 LLLSQHNFAPIVTPSVTSSIPSWQQSATP 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex14	NP_649253.1	Pex14_N	34..145	CDD:282540	32/115 (28%)
prx-14	NP_502097.1	Pex14_N	10..>58	CDD:368060	16/52 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2629
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I3943
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004737
OrthoInspector	1	1.000	-	-		oto19224
orthoMCL	1	0.900	-	-		OOG6_105746
Panther	1	1.100	-	-	LDO	PTHR23058
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R901
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.830