DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex16 and pex16

DIOPT Version :9

Sequence 1:	NP_649252.1	Gene:	Pex16 / 40293	FlyBaseID:	FBgn0037019	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001020340.1	Gene:	pex16 / 573990	ZFINID:	ZDB-GENE-050626-49	Length:	335	Species:	Danio rerio

Alignment Length:	348	Identity:	125/348 - (35%)
Similarity:	205/348 - (58%)	Gaps:	23/348 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTLKGMLKAYEAWVGKNPDVVGDFETTAKWVSYFIAGRISSSNVVSELVYTLSNMLVFYNDRII 65
            |:.|..:.:.|:.:|..:|......|:|.:.:||.||||.|.|:.:|||||:.||:||..||.|:
Zfish     1 MEKLTRVFERYQEYVRTSPAAASHLESTVRALSYLIAGRFSDSHEISELVYSASNLLVLLNDGIL 65

  Fly    66 EKARNSEENSVIHLQSKLCYRLKVTLTTLEYSEVFIEISARRLFGQSGKWLVIALIQAFKAAGRF 130
            .|..:......|..|..|.:     |:.|||.|||:|::|.:::|.:|:||||.|||..||..|.
Zfish    66 RKNLSRTLPMSISQQKLLTW-----LSVLEYVEVFVEMAAAKMWGDAGRWLVIVLIQIAKAVLRC 125

  Fly   131 FILKHSTSDIITSPPIAALNRRAKQRKNSGDGVASSTNDLLQSQHSITFQLKRSGRVIRKVEGAP 195
            .:|....|.|.|||||..|:|.::        :.|..|:..:.....:|..:|||||:|.:..||
Zfish   126 LLLFWYKSGIQTSPPIIPLDRDSQ--------LCSQDNNEEEDDEDSSFVGQRSGRVVRPLGSAP 182

  Fly   196 PLQYRDF----KLHIDNNE-----AAKTQIPRKLLQAEYLYISKPLIHLVAMGLFGRRSWKQYMV 251
            .||.|.:    |..:..|:     ::.|.:..:...||.|||::||:||.::|:.|:||||.:::
Zfish   183 SLQSRLWGLPRKKKVSRNQEEELHSSPTPLGLQETIAESLYIARPLLHLASLGICGKRSWKPWIL 247

  Fly   252 ALSIDLYSIHLYRQHRDLMSKQQKLELSRRCINIMYFLVRSPFYDSFTKSRLERILDFVATSVPI 316
            :..:::.|..|....:.| :::::.|:.||...::|:|:||||||.::::::..:|.|:|..||.
Zfish   248 SGLLEITSFSLLSDMKAL-NRRERAEMRRRAFLLLYYLLRSPFYDRYSETKILFLLRFLADYVPG 311

  Fly   317 AKVVAKPLKDYIPTWQSTYFYLW 339
            ..:||:||.:|:|.||..|||.|
Zfish   312 VGLVARPLMEYLPIWQKIYFYNW 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex16	NP_649252.1	Pex16	11..333	CDD:285774	118/330 (36%)
pex16	NP_001020340.1	Pex16	11..328	CDD:285774	118/330 (36%)
		Required for peroxisomal location. /evidence=ECO:0000250\|UniProtKB:Q9Y5Y5	66..81		2/14 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..168		4/29 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590492
Domainoid	1	1.000	201	1.000	Domainoid score	I2974
eggNOG	1	0.900	-	-		E1_KOG4546
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3537
Inparanoid	1	1.050	214	1.000	Inparanoid score	I3609
OMA	1	1.010	-	-		QHG58411
OrthoDB	1	1.010	-	-		D344611at33208
OrthoFinder	1	1.000	-	-		FOG0006249
OrthoInspector	1	1.000	-	-		oto40898
orthoMCL	1	0.900	-	-		OOG6_103805
Panther	1	1.100	-	-	LDO	PTHR13299
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5562
SonicParanoid	1	1.000	-	-		X5194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	16	15.840