DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex16 and pex16

DIOPT Version :9

Sequence 1:	NP_649252.1	Gene:	Pex16 / 40293	FlyBaseID:	FBgn0037019	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001120111.1	Gene:	pex16 / 100145130	XenbaseID:	XB-GENE-1011467	Length:	340	Species:	Xenopus tropicalis

Alignment Length:	357	Identity:	121/357 - (33%)
Similarity:	189/357 - (52%)	Gaps:	43/357 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DTLKGMLKAYEAWVGKNPDVVGDFETTAKWVSYFIAGRISSSNVVSELVYTLSNMLVFYNDRIIE 66
            |.|:.:.:.|:.:|.:||......|:..:.:||.||||.:.|:.:|||||:.||:|...||.|:.
Frog     7 DKLQDLSQKYKDYVIQNPTGATQLESAVRMLSYLIAGRFADSHELSELVYSASNLLALLNDGILR 71

  Fly    67 K---ARNSEENSVIHLQSKLCYRLKVTLTTLEYSEVFIEISARRLFGQSGKWLVIALIQAFKAAG 128
            |   |....|.|        ..||...|..||..||||||.|.|.:|...:|..|.:||..||..
Frog    72 KELLAPPPTEGS--------RRRLLTWLGVLESLEVFIEIGAARAWGDRTRWAAILIIQLLKACL 128

  Fly   129 RFFILKHSTSDIITSPPIAALNR-----RAKQRKNSGDGVASSTNDLLQSQHSITFQLKRSGRVI 188
            |..:|....:.|.:|||:..|:|     :|:...|||               |..|..:||.|.:
Frog   129 RIVLLFWYRAGIQSSPPVTPLDREGILNQAEDNSNSG---------------SSCFVGRRSSRAV 178

  Fly   189 RKVEGAPPLQ---YRDFKLH------IDNNEAAK--TQIPRKLLQAEYLYISKPLIHLVAMGLFG 242
            |.::.:....   :|..::|      ....|:.|  :::......||.::|.:|:.||:::..:|
Frog   179 RSLDDSASSHRRFWRSPQIHDGKQRNTGETESDKDGSELGTLGTLAEAIHILRPITHLLSLATWG 243

  Fly   243 RRSWKQYMVALSIDLYSIHLYRQHRDLMSKQQKLELSRRCINIMYFLVRSPFYDSFTKSRLERIL 307
            ::|||.:|||.::|:.||.|....|:| |.:::.||.||...::|:|:|||||:.:|::||..:|
Frog   244 QKSWKPWMVAAALDITSISLLSDVRNL-SHRERAELRRRMFLLLYYLLRSPFYNHYTETRLLLLL 307

  Fly   308 DFVATSVPIAKVVAKPLKDYIPTWQSTYFYLW 339
            ..:...||...:||:||.||:|.||..|||.|
Frog   308 RLLGDYVPGVGLVARPLMDYLPVWQKIYFYNW 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex16	NP_649252.1	Pex16	11..333	CDD:285774	114/340 (34%)
pex16	NP_001120111.1	Pex16	16..333	CDD:285774	114/340 (34%)
		Required for peroxisomal location. /evidence=ECO:0000250\|UniProtKB:Q9Y5Y5	71..86		4/22 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..216		3/19 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3782
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3537
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3867
OMA	1	1.010	-	-		QHG58411
OrthoDB	1	1.010	-	-		D344611at33208
OrthoFinder	1	1.000	-	-		FOG0006249
OrthoInspector	1	1.000	-	-		otm48811
Panther	1	1.100	-	-	LDO	PTHR13299
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5562
SonicParanoid	1	1.000	-	-		X5194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110