DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pitslre and AT1G67580

DIOPT Version :9

Sequence 1:	NP_649251.2	Gene:	Pitslre / 40292	FlyBaseID:	FBgn0016696	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001154456.1	Gene:	AT1G67580 / 843079	AraportID:	AT1G67580	Length:	752	Species:	Arabidopsis thaliana

Alignment Length:	792	Identity:	289/792 - (36%)
Similarity:	405/792 - (51%)	Gaps:	153/792 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 RSSKYAESKDAESLEQDLRSRLLKKRHNYVKDYETEENYEH--------------RVERSDR--- 228
            |:.:|   .|.|..:|:..||..::...|     ..|:|.|              .:...||
plant     5 RNIRY---PDHELRDQESNSRFSRRDSAY-----ANEDYNHVRNGAIDNGKGRVSNLRHGDRDRI 61

  Fly   229 REGGRKERERTVRS---THKQNRHDRVIELLDSPEQEHHHQHQHKSHRSKWREEVEVIRRKVPED 290
            :.|.|:|..:.|.|   ..|.|...|.:.:...|::...      |.||..||..|:......:|
plant    62 KSGARQEENKMVSSGFRLSKSNPGSREVFIDLGPKRCGF------SARSVDREPGELSSESGSDD 120

  Fly   291 L---ELLARREKLLAAERESRQRKQTAREELEARRELLRERNEHSDA-------------LSP-- 337
            |   |.||   |:....:|...|.|:..|:......::.:|::|..:             |.|
plant   121 LIESESLA---KVNGVVKEVENRAQSPVEKKRKFSPIVWDRDDHERSNLSRNEKPVEVTPLPPPP 182

  Fly   338 -----TTVAASVTAGLNIHVKRKSKPDNYEKEIKLKKRR------------------EDDIEVIR 379
                 ::.:.||:.|.|.|.. .:|.|.::..:::....                  |......:
plant   183 PLVKRSSQSPSVSCGGNSHYS-PAKSDMHQDPVEVGVSAVSMPALSPSVEMSSLCVVEQSSNAEQ 246

  Fly   380 DDDDEESEESDSNEEVPEQDSEGSATESGSEDSYASKKKSKIKSKSQLEDDDEDLPLPDSPLSVG 444
            ||..|.:...:.:|.:|.:....|...:|:..                         |...:.:.
plant   247 DDKQEHATHLEEDENMPTRHISSSRWAAGNSS-------------------------PTDEVEIV 286

  Fly   445 ELYKSPKQRQRSRSVSSKSSSQSSRSSRSRSRSRSQSSLEDEV--------DRQDVGADASPSSS 501
            |.....|:|::...|            :.|.|:.||:....|:        |..:.|..:.|.|.
plant   287 EEVGEKKRRKKPFPV------------QGRFRNTSQTPEVGELVREGYRSSDSDERGHHSLPGSR 339

  Fly   502 TRSEERGMTQEQPEEKPEEKLKEKQK--SLEEQIPCDDKGI----PLPNYYP-----GVQGCRSV 555
            ...|||...:....|..||:.:.:..  ||.| ...||:.:    |.|...|     .:||||||
plant   340 DDFEERDAVKSDKMEIDEEEHRRENSVDSLSE-TDSDDEYVRHETPEPASTPLRSINMLQGCRSV 403

  Fly   556 EEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTV 620
            :||:.||:|:|||||||||||||:|.||||||::|||||:||||:|||||||.||...||:||.|
plant   404 DEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDV 468

  Fly   621 REIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRD 685
            :|:||||::|.||:||:|:|||||:||||||.|   |...|||||..|||..|.:|||||:||||
plant   469 KEVVVGSSLDSIFMVMEYMEHDLKALMETMKQR---FSQSEVKCLMLQLLEGVKYLHDNWVLHRD 530

  Fly   686 LKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCI 750
            ||||||||:::|.||:.||||||:||||:|.||.||||||||||||||.:..|||.||:||:|||
plant   531 LKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCI 595

  Fly   751 FAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKH 815
            .||.|...|||.||:|.|:|::||:.||||||.||||:::||.||      ..|.::..:.|||.
plant   596 MAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVK------VNFVKHQYNLLRKK 654

  Fly   816 FQEKT-------SEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSMFPTWPAKSELG 873
            |...:       |:.|..||..||||||::|::.:.||||.:|:|:|||......||:||:....
plant   655 FPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFREVPLPKSKDFMPTFPAQHAQD 719

  Fly   874 AR-KAQASSPKP 884
            .| :....||.|
plant   720 RRGRRMVKSPDP 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	189/305 (62%)
Pitslre	NP_649251.2	PLN00009	555..854	CDD:177649	187/305 (61%)
AT1G67580	NP_001154456.1	STKc_CDC2L1	400..697	CDD:173741	189/305 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	367	1.000	Domainoid score	I183
eggNOG	1	0.900	-	-		E1_KOG0663
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	1	1.000	-	-		FOG0001516
OrthoInspector	1	1.000	-	-		otm2460
orthoMCL	1	0.900	-	-		OOG6_102464
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2585
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780