Protein Alignment Pitslre and prpf4ba

DIOPT Version :10

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: XP_017207374.1
• Gene: prpf4ba / 393182
• ZFINID: ZDB-GENE-040426-947
• Length: 986
• Species: Danio rerio
• Alignment Length: 1050
• Identity: 217/1050 - (20%)
• Similarity: 358/1050 - (34%)
• Gaps: 365/1050 - (34%)

  Fly    52 RREKKKHSRERRRHK-----ERDDVGGAALALERDHRYDYRSREEHYHHHQRERSSNAAAAYAKH 111
            ::.|.||..:.::||     |||          :.|:|.::.:.:|....:.:|..:.
Zfish    52 KKRKHKHRSKHKKHKHSSPDERD----------QKHKYKHKHKRKHRDSFRDDRECST------- 99

  Fly   112 HLGHAYHYPQPPQQQQQPLPPAPSYAAHHYHHHQHLSGARAAPREYH------------------ 158
                                   ||           .||..:|:.:.
Zfish   100 -----------------------SY-----------EGAADSPKRFRLDDLAALEDLEKQRAMIQ 130

  Fly   159 ----------SYPS-------GYHSGSRHGDYPMEEPTRRSSKYAESKDAESLEQDLRSRLLKKR 206
                      |..|       ||:|.|..|:  ::|..|...:  :.||.:.| ..::....|.:
Zfish   131 AELDNELMEGSVQSGMGLILQGYNSDSEDGE--VQEAVRNGEQ--QRKDLDEL-VTVKGNGRKLQ 190

  Fly   207 HNYVKDYETEENYEHRVERSDRREGGRKERERTVRSTHKQNRHD-------RVIELLDSPEQEHH 264
            .:||.|   |:.|       ...||.....|.||:| ||..:.:       ::.|....|.:...
Zfish   191 QDYVND---EQFY-------SVLEGRTMSEEVTVQS-HKSEKRESMTGLGIKISERPSGPSETKE 244

  Fly   265 HQHQHKSHRSK---WREEVEVIRRKVPEDLELLARR------EKLLAAERESRQRKQTAREELEA 320
            .:....:.|||   .|.:..|..::||.......|:      |:.:.....||..|..::|...:
Zfish   245 RRRSRSTDRSKDRSRRSKSPVKSKEVPSSSATSNRKSNTRPEEQAVDHRSSSRSSKSGSKERSTS 309

  Fly   321 RRELLRERNEHSDALSPTTVAASVTAGL-NIHVKRKSKPDNYEKEIKLKKRREDD-IEVIRDDDD 383
            ..|:.|::......|.      .|::|. |....||..||.....::.:..|..: :.|:::.|.
Zfish   310 LPEVDRDKKPVKAPLK------EVSSGKENRSPSRKQGPDRLSPTVQPRSHRSPERLPVVQNTDR 368

  Fly   384 EESEESDS--NEEVPEQDSEGSATESGSEDSYASKKKSKIKSKSQLEDDDEDLP-------LPDS 439
            ...::..:  |...|.:....|......|:........:::|:.......||.|       |..|
Zfish   369 ASRQDRSTCHNRSPPRRGRSRSVERRRREEERQRLSSDRMRSRDMAGAHREDSPSISSRRRLNHS 433

  Fly   440 PLSVGELYKSPKQRQRSRSVSSKSS-------------------SQSSRSSRSRSRSR------- 478
            ||           |:||||...:||                   |:|....|.||:.|
Zfish   434 PL-----------RRRSRSPRRRSSRSPLRHRERDRMDRRQPVRSRSQERRRRRSKEREDMFKGS 487

  Fly   479 ------------SQSSLED-EVDRQD---------------------VGADA---------SPSS 500
                        .:..||| :||.:|                     |..|:         ||.|
Zfish   488 LSEGMKAEQEDSDEEVLEDYDVDEEDEEALIEQRRLQRLAIMQKYKPVNEDSNMSGLSDHGSPQS 552

  Fly   501 STRSE--------ERGMTQEQPEEKP-----EEKLKEKQKSL-EEQIPCDDKGIPLPNYY----- 546
            ||.|.        ||.....:..|:.     |:.:|.|...: :|:...:.|..|.|:.:
Zfish   553 STHSRSPSPDDILERVAADVKAYEQENLDTFEDNVKAKYSLVSQEKNGANSKKPPAPDMFTESDD 617

  Fly   547 -----------------------PGV-------QGCRSVEEFQCLNR-------IEEGTYGVVYR 574
                                   |.:       :|...|...:.|::       ..:|.:..|.|
Zfish   618 MFAAYFDSARLRAAGIGKDFKENPSLRDNWTDAEGYYRVNIGEVLDKRYAVYGYTGQGVFSNVIR 682

  Fly   575 AKD-KRTNEIVALKRLK----MEKEKEGFPITSLREINTLLK---------------------GQ 613
            |:| .|.|:.||:|.::    |:|       |.|:|:..|.|                     .|
Zfish   683 ARDLARANQEVAVKIIRNNEMMQK-------TGLKELEFLKKLNDADADDKFHCLRLFRHFYHKQ 740

  Fly   614 HPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPG----EVKCLTQQLLRAVA 674
            |                 :.:|.:.:..:|:.::     ||.....|    .|:..:|||..|:.
Zfish   741 H-----------------LCLVFEPLSMNLREVL-----RKYGKDVGLHIKAVRSYSQQLFLALK 783

  Fly   675 HLHDNWILHRDLKTSNLLLSH-KGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVY 738
            ||....|||.|:|..|:|::. |.|||:.|||.|.....  ...|..:|:.:|||||::: ...|
Zfish   784 HLKRCNILHADIKPDNILVNEPKTILKLCDFGSASHVAD--NDITPYLVSRFYRAPEIII-GKSY 845

  Fly   739 STPIDVWSVGCIFAEFLQMLPLFPGK--SEIDELNRIFKELGTPNEKIWPG-------------- 787
            ...||:|||||...|......|||||  :.:.:||...|. ..||:.|..|
Zfish   846 DYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLNMDLKG-KLPNKMIRKGLFKDQHFDQNLNFL 909

  Fly   788 YTELPAVKNMLSQNSQFTEYPVSQLRKHF-------QEKTSEMG--LSLLQGLLTYDPKQRLSAD 843
            |||:..|..........|..|...|....       :::..::|  ..||..:|..||.:|::.:
Zfish   910 YTEVDKVTEREKITVMSTINPTKDLSMDMVGRQALPEDQRKKVGQLKDLLDQILMLDPAKRITIN 974

  Fly   844 AALKHGFFKE 853
            .||:|.|.:|
Zfish   975 QALQHPFIQE 984

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	93/361 (26%)
prpf4ba	XP_017207374.1	STKc_PRP4	665..982	CDD:271037	91/349 (26%)