Protein Alignment Pitslre and Cdk13

DIOPT Version :9

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: XP_038951649.1
• Gene: Cdk13 / 306998
• RGDID: 1311226
• Length: 1527
• Species: Rattus norvegicus
• Alignment Length: 1125
• Identity: 276/1125 - (24%)
• Similarity: 424/1125 - (37%)
• Gaps: 338/1125 - (30%)

  Fly     4 SSGSEDGQLRSPNDVHYHSRGEEDEHEGDADALYIQPPQASRESGSGPRREKKKHSRERRRHKER 68
            ::|...|...||..    |.|.:...||..     :.|:..|.|.||  |.|::|    |.|:.|
  Rat   170 AAGGTGGNGGSPAS----SSGTQRRAEGSE-----RRPRRDRRSSSG--RSKERH----REHRRR 219

  Fly    69 DDVGGAALALERDHRYDYRSREEHYHHHQ----------------RERSSNAAAAYA-------- 109
            |.....:.|        .::|..|.|..:                |.:|::|.::.:
  Rat   220 DGTRSGSEA--------SKARSRHGHSGEERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDL 276

  Fly   110 KHHLGHAYHYPQPPQQQQQPLPPAPSYAAHHYHHHQHLSGARAAPREYHSYPSGYHSGSRHGDYP 174
            |.|........:||...::|    |.                 |.||..|.|..|.
  Rat   277 KAHRSRTKSSKEPPSAYKEP----PK-----------------AYREDKSEPKAYR--------- 311

  Fly   175 MEEPTRRSSKYA------ESKDAESLEQDLRSRLLKKRHNYVKDYETEENYEHRVERSDRREGGR 233
                 ||....:      ||..:....|.||||                       :|....||.
  Rat   312 -----RRQRSLSPLGGRDESPVSHRASQSLRSR-----------------------KSPSPAGGG 348

  Fly   234 KE--RERTVRSTHKQNRHDRVIELLDSPEQEHHHQHQHKS-------HRSKWREE----VEVIRR 285
            ..  ..|..||....:|.       .||....|..::...       ..|.||..    ..|:||
  Rat   349 SSPYSRRLPRSPSPYSRR-------RSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRR 406

  Fly   286 KVPEDLELLARREKLLAAERESRQRKQTAREELEARRELLRERNEHSDALSPTTVA--ASVTAGL 348
            ....       |.:...:.|.||.|         :|..|.|.|:.|| ::||:|:.  :|:.|.|
  Rat   407 SAKS-------RSRSPYSSRHSRSR---------SRHRLSRSRSRHS-SISPSTLTLKSSLAAEL 454

  Fly   349 NIHVKRKSKPDNYEKEIKLKKRREDDIEVIRDDDDEESEESDSNEEVPEQDSEGSA--------T 405
            |                |.||.|.  .|..|..:..::.|:....|...:.::.|:        |
  Rat   455 N----------------KNKKARA--AEAARAAEAAKAAEAAKAAEAAAKAAKASSVSTPTKGNT 501

  Fly   406 ESGSEDSYASKKKSKIKSKSQLEDDDEDLPLPDSPLSVGELYKSPKQRQRSRSVSSKSSS----- 465
            |:|:..|..:..|...|.|:      |..|.|.|    |...||.|.:.:.....:|..:
  Rat   502 ETGASVSQTNHVKEVKKLKT------EHAPSPSS----GGTVKSDKTKTKPPLQVTKVDNNLIVE 556

  Fly   466 QSSRSSRSRSRSRSQSSLEDEVDRQDVGADASPSSSTRSEER------------GMTQEQPEEKP 518
            ::::.:.....|:..::.|:.|..::.....:||...:.:|:            .:....||:|.
  Rat   557 KATKKTVVGKESKPAATKEEPVSTKEKTKPLTPSVGAKEKEQHVALVTSTLPPLPLPPMLPEDKD 621

  Fly   519 EEKL------KEKQKSLEEQIPCDDKGIPLPNYYPGVQ--------------------------- 550
            .:.|      |..:|.:|:::.|....:|||...||..
  Rat   622 ADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPR 686

  Fly   551 -----------GCRSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLR 604
                       |.|.|::|..:..|.|||||.||:|:||.|.|:||||:::::.||||||||::|
  Rat   687 YGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIR 751

  Fly   605 EINTLLKGQHPNIVTVREIVVGS------NMDK--IFIVMDYVEHDLKSLMETMKNRKQSFFPGE 661
            ||..|.:..|.:|:.::|||...      ..||  .::|.:|::|||..|:|   :....|....
  Rat   752 EIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLE---SGLVHFNENH 813

  Fly   662 VKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGS-PIKKYTSLVVTLW 725
            :|...:||:..:.:.|....||||:|.||:||:::|.:|:.||||||.|.| ..:.||:.|:|||
  Rat   814 IKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLW 878

  Fly   726 YRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTE 790
            ||.|||||....|:..|||||.|||..|.....|:|....|:.:|..|.:..|:|...:||...:
  Rat   879 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIK 943

  Fly   791 LPAVKNMLSQNSQFTEYPVSQLRKHFQEK---TSEMGLSLLQGLLTYDPKQRLSADAALKHGFFK 852
            ||....|         .|..|.|:..:|:   .....|.|...:|..||.:|.:|:.||:..|.:
  Rat   944 LPYFNTM---------KPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999

  Fly   853 ELPLPIDPSMFP----------------------------TWPAKS------------------- 870
            :    ::||..|                            .|..|.
  Rat  1000 D----VEPSKMPPPERFLHAEAMHHSKMAESLPLWQDCHELWSKKRRRQKQMGMTDDLSTIKAPR 1060

  Fly   871 ---ELGARKAQASSPK---PPSGGSQFKQLGRDE--PIIVGPGNKL--SSGIITGNKKSHGAGGS 925
               .||...::.|:|:   ||   :|.|......  |:|.|||..|  |...|..|.....:..:
  Rat  1061 KDLSLGLDDSRTSTPQGVLPP---AQLKSQNSSSGAPVITGPGQPLNHSELAILLNLLQSKSSVN 1122

  Fly   926 SASTGFVLNAGI---TQRQL 942
            .|....|||..:   ||:||
  Rat  1123 MADFVQVLNIKVNSETQQQL 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	118/310 (38%)
		PLN00009	555..854	CDD:177649	118/310 (38%)
Cdk13	XP_038951649.1	STKc_CDK12	697..998	CDD:270847	119/312 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920