Protein Alignment Pitslre and cdk-11.2

DIOPT Version :9

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_509746.2
• Gene: cdk-11.2 / 181247
• WormBaseID: WBGene00013917
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 253/719 - (35%)
• Similarity: 360/719 - (50%)
• Gaps: 150/719 - (20%)

  Fly   210 VKDYETEENYEHRVERSDRREGGRKERERTVRSTHKQNRHDRVIELLDSPEQEHHHQHQHKSHRS 274
            :.:|.|..:.:.|:..||      .:...|..|...:|.|....|.....|:|..|:..|...|
 Worm     1 MSNYSTNGSRKIRISNSD------DDSRETRFSIQPRNSHKTKEERYRDKEKERDHERHHDRER- 58

  Fly   275 KWREEVEVIRRKVPEDLELLARREKLLAAERESRQRKQTAREELEARRELLRERNEHSDALSPTT 339
              |::                |..|:.:.:...|.|:..|......|.|..|.||.|||
 Worm    59 --RDD----------------RYRKVDSRDHRDRNRRSPAGSRTYCRDEPDRRRNNHSD------ 99

  Fly   340 VAASVTAGLNIHVKRKSKPDNYEKEIKLKKRREDDIEVIRDDDDEESEESDSNEEVPEQDSEGSA 404
                                        :.||           |..||.        ::|:..|.
 Worm   100 ----------------------------RNRR-----------DRSSER--------DRDNRSSK 117

  Fly   405 TESGSEDSYASKKKSKIKSKSQLEDDDEDLPLPDSPLSVGELYK---SPKQRQRSRSVSSKSSSQ 466
            :::.|.||..||...|.::.:.|.||             |:|:.   .|..:::.::|......:
 Worm   118 SKTKSPDSLRSKSSRKSQTPNHLPDD-------------GKLFDRILDPNYKKKEKTVMEVEDVE 169

  Fly   467 SSRSSRSRSRSRSQSSLED---------EVDRQDVGADASPSSSTRSEERGMTQE---------- 512
            .|..........|..:.:|         |.:.:|..::..|.|...:.:..:|.:
 Worm   170 MSPVEMLDEEEVSTFTFDDACGPVRPSNEPEEKDYKSEGDPESRPATPKTPLTPDYLENTIVSLN 234

  Fly   513 ----QPEEK-PEEKL-----KEKQKSL---EEQIPCD-----------DKGIPLPNYYPGVQGCR 553
                ..|:| |::|.     ||:.:|:   |:::..|           :....||.||||::||:
 Worm   235 ETLSDDEDKGPDDKYGKTPDKEQWESMTENEQKLHRDAMKKRREQRHREAVSKLPVYYPGLRGCQ 299

  Fly   554 SVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLK-GQHPNI 617
            .:.|:..||.|.|||||.|:|.|:.||:|:|||||.||||||||||||:|||||.||| |.|.||
 Worm   300 HISEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENI 364

  Fly   618 VTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWIL 682
            |.|:||:|||...::::.|:|||||:|||::.|::|.|.|..|:.|.|..|||..:.|:|..|||
 Worm   365 VNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIEHMHKLWIL 429

  Fly   683 HRDLKTSNLLLSHKGILKVGDFGLAREYG-----SPIKKYTSLVVTLWYRAPELLLCSPVYSTPI 742
            ||||||||||:||.||||:.|||||||||     ....|.|.:|||||||:|||||....||||:
 Worm   430 HRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPV 494

  Fly   743 DVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEY 807
            |:||:|||.|||:.|.|:|.|.||.:::::||:.:|||.|:|||...|| .|.||:    :|...
 Worm   495 DMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKEL-KVWNMV----EFPPV 554

  Fly   808 PVSQLRKHFQ-EK-TSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSMFPTWPAKS 870
            ...|||:.|: || .:|.|..||.|:|..:|..||:|..||:|.:|.|.|..:.|...|.:||||
 Worm   555 KPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFSEHPKAVPPEDLPVYPAKS 619

  Fly   871 ELGA 874
            ||.|
 Worm   620 ELNA 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	168/306 (55%)
		PLN00009	555..854	CDD:177649	168/306 (55%)
cdk-11.2	NP_509746.2	PKc_like	298..600	CDD:389743	168/306 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	383	1.000	Domainoid score	I432
eggNOG	1	0.900	-	-		E1_KOG0663
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	474	1.000	Inparanoid score	I822
Isobase	1	0.950	-	0	Normalized mean entropy	S790
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	1	1.000	-	-		FOG0001516
OrthoInspector	1	1.000	-	-		otm14318
orthoMCL	1	0.900	-	-		OOG6_102464
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2585
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.780