Protein Alignment Pitslre and cdk-9

DIOPT Version :10

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_492906.2
• Gene: cdk-9 / 173023
• WormBaseID: WBGene00000410
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 154/492 - (31%)
• Similarity: 226/492 - (45%)
• Gaps: 81/492 - (16%)

  Fly   469 RSSRSRSRSRSQSS-LEDEVDRQDVGADASPSSSTRSEERGMTQEQPEEKPEEKLKEKQKSLEEQ 532
            :||..|...|..:. .::...|..:|...:||||...:....|..:.|.|  ::|...||..::.
 Worm    12 QSSTQRPPKRPNTEHAQEPPKRALIGGQTTPSSSGGGQTPNGTNYELEVK--QQLSNYQKLFDQA 74

  Fly   533 IPCDDKGIPLPNYYPGVQGCRSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEG 597
            .            ||.:   |.|..::.||:|.:||:|.|::|:.|.|..:||||::.||.||||
 Worm    75 T------------YPFI---RDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEG 124

  Fly   598 FPITSLREINTLLKGQHPNIVTVREIV----VGSNMDK----IFIVMDYVEHDLKSLMETMKNRK 654
            ||||:|||:..|.:.:||||..:.|:.    .|:...|    .::||....|||..|:...|.|.
 Worm   125 FPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRM 189

  Fly   655 QSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREY------GSP 713
            ...   .:|.:.:.|:..:..||.:.|||||:|.:|:|:|..||||:.||||||.:      ..|
 Worm   190 SLV---HIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGP 251

  Fly   714 IKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELG 778
            ...||:.|||||||.|||||....|.|.||||..|||.||.....|:..|.:|..:|..|....|
 Worm   252 RPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCG 316

  Fly   779 TPNEKIWPGYTELPAVKNMLSQ-NSQFTE--Y---------------------PVSQLRKHFQEK 819
            :.|:.:||....:|....|.|: ||...:  |                     |..:..|.....
 Worm   317 SINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSA 381

  Fly   820 TSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLP----------IDPSMFPTWPAKSELGA 874
            |.:..|.||:.||..||.:|.::|.|....:|.:.|:|          |..|.|.....|.....
 Worm   382 TDDDALHLLEILLAIDPDKRPTSDEAEDDIWFFKDPVPMANVQDLMDTIPNSQFEYTVGKGAHAN 446

  Fly   875 RKAQASSPKPPSGGSQFKQLGRDEPIIVGPGNKLSSG 911
            |....::.:.|:     :|..|       |.|.:.:|
 Worm   447 RGRHQNAQQRPN-----QQQAR-------PSNAIPAG 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	122/336 (36%)
cdk-9	NP_492906.2	STKc_CDK9	72..413	CDD:270848	124/358 (35%)