Protein Alignment Pitslre and CDK3

DIOPT Version :10

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 140/346 - (40%)
• Similarity: 201/346 - (58%)
• Gaps: 57/346 - (16%)

  Fly   555 VEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVT 619
            ::.||.:.:|.||||||||:||::.|.::||||:::::.|.||.|.|::|||:.|.:.:|||||.
Human     1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVR 65

  Fly   620 VREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGE------VKCLTQQLLRAVAHLHD 678
            :.::|  .|..|:::|.:::..|||..|::.        ||.      :|....|||:.|:..|.
Human    66 LLDVV--HNERKLYLVFEFLSQDLKKYMDST--------PGSELPLHLIKSYLFQLLQGVSFCHS 120

  Fly   679 NWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPID 743
            :.::|||||..|||::..|.:|:.||||||.:|.|::.||..||||||||||:||.|..|:|.:|
Human   121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVD 185

  Fly   744 VWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYP 808
            :||:||||||.:....||||.||||:|.|||:.||||:|..|||.|:||..|.         .:|
Human   186 IWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG---------SFP 241

  Fly   809 VSQLRKHFQEKTSEM---GLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSMFPTWPAKS 870
             ...||..:|....:   |..||..||.|||.||::|..||.|.:|
Human   242 -KWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF------------------- 286

  Fly   871 ELGARKAQASSPKPPSGGSQF 891
                     |||:|.....|:
Human   287 ---------SSPEPSPAARQY 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	134/304 (44%)
CDK3	NP_001249.1	STKc_CDK2_3	3..286	CDD:270844	134/302 (44%)