Protein Alignment Pitslre and cdk13

DIOPT Version :9

• Sequence 1: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: XP_002940845.2
• Gene: cdk13 / 100489599
• XenbaseID: XB-GENE-6040279
• Length: 1391
• Species: Xenopus tropicalis
• Alignment Length: 1042
• Identity: 264/1042 - (25%)
• Similarity: 411/1042 - (39%)
• Gaps: 230/1042 - (22%)

  Fly    43 ASRESGSGP------RREKKKHSRERRRHKER---------------DDVGGAALALERDHRYDY 86
            ||..||..|      |:.:..|.|::||.:::               ||...|.
 Frog    20 ASSVSGQHPGPADDSRKRRSHHQRKKRRARQQAMLDCSVEPVGPTDGDDSQAAT----------- 73

  Fly    87 RSREEHYHHHQRE---------------RSSNAAAAYAKH---------HLGHAYHYPQPP---- 123
            |.|..|..|.:|:               |...|.|...::         .|......|.||
 Frog    74 RGRRHHRMHRERKKRRKDRGGSGRRSGLRKDRARAPTVEYDDVSSLSDGDLSEGEQVPTPPFAPS 138

  Fly   124 ------------QQQQQPL---PPAPSYAAHHYHHHQHLSGARAAPREYHSYPSGYH-------- 165
                        .:...|:   ||.|..:..........||.|...|.    |...|
 Frog   139 VLGLGLNASPASDRCPSPVGLPPPPPQVSLLRQRGDSGRSGRRKTSRR----PESKHRRREDMQD 199

  Fly   166 --SGSRHGDYPMEEPTRRSSKYAESKDAESLEQDLRSRLLKKRHNYVKDYETE--ENYEHRVERS 226
              .|...||..:..|...:|.:....:.....:.....|.:.:......|..:  :.|..:..||
 Frog   200 RRRGGEIGDLLLPTPLMLASTWRPQCELGKKPEFRPVPLFRPKREEALAYNKQPPKAYRDKGFRS 264

  Fly   227 DRREGG-RKERERTVRST------HKQNRHDRVIELLDSPEQEHHHQHQHKSHRSKWREEVEVIR 284
            ...:|. ||:....|||.      |:|||......:.|..|.....:.:.:|..|.........|
 Frog   265 SVLQGNHRKKSLSPVRSPSPGYSGHRQNRRSPSFGVRDKNETSPPARRRSRSPYSPGGRRTARSR 329

  Fly   285 RKVPEDLELLARREKLLAAERESRQRKQTAREELEARRELLRERNEHSDALSPTTVAASVTAG-L 348
            .:.|........|.:...::..||| ...:..:|..:..|..|.|::..|.......|...|| :
 Frog   330 SRSPYKPRHSRSRSRHRGSKSRSRQ-SSISPSKLTLKSSLAAELNKNKKAREAEAARAQAKAGKI 393

  Fly   349 NIHVK------RKSKPDNYEKEIKLKKRREDDIEVIRDDDDE-----ESEESDSNEEVPEQDSEG 402
            :..||      ..|:..|..||  .||.:.|.::......::     :|:||.....:|.:.:..
 Frog   394 STPVKGQLEAVSNSQQSNTAKE--QKKVKTDRVQSPSQKSEKAKVKVQSQESCRENNLPAEKTAK 456

  Fly   403 SATESG-----SEDSYASKKKS-----------KIKSKSQLEDDDEDLPLPDSPLSVGELYKSPK 451
            |:::..     .:::..||:|:           |||..:.|......||||....|.||.::.
 Frog   457 SSSKVSKIDLVKQETCTSKEKAKTHNSDAATTEKIKCLALLTSALPSLPLPPVLSSHGESFRG-- 519

  Fly   452 QRQRSRSVSSKSSSQSSRSSRSRSRSRSQSSLEDEVDRQ------DVGADASPSSSTRSEERGMT 510
                  .|..|                   |::.|::|:      |:.....|:..:.||:   .
 Frog   520 ------CVPGK-------------------SVKKEMERKLRTLLSDLPLPPLPAPQSESED---V 556

  Fly   511 QEQPEEKPEEKLKEKQ---------KSLEEQIPCDDKGIPLPNYYPGVQGCRSVEEFQCLNRIEE 566
            .:.||.|..:...:::         :.||::|.               .|.|.|::|..:..|.|
 Frog   557 SDSPERKKNQSRNKRRPKICGPRCGEILEKEID---------------WGKRCVDKFDIIGIIGE 606

  Fly   567 GTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVREIVVGS---- 627
            ||||.||:||||.|.|:||||:::::.||||||||::|||..|.:..|.:|:.::|||...
 Frog   607 GTYGQVYKAKDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLNHQSIINMKEIVTDKEDAL 671

  Fly   628 --NMDK--IFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKT 688
              ..||  .::|.:|::|||..|:|   :....|....:|...:||:..:.:.|....||||:|.
 Frog   672 DFKKDKGAFYLVFEYMDHDLMGLLE---SGLVHFNEHHIKSFMRQLMEGLDYCHKRNFLHRDIKC 733

  Fly   689 SNLLLSHKGILKVGDFGLAREYGS-PIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFA 752
            ||:||:::|.:|:.||||||.|.| ..:.||:.|:|||||.|||||....||..|||||.|||..
 Frog   734 SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILG 798

  Fly   753 EFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQ 817
            |.....|:|....|:.:|..|.:..|:|...:||...:||....|         .|..|.|:..:
 Frog   799 ELFTKKPIFQANQELAQLELISRMCGSPCPAVWPDVIKLPYFNTM---------KPKKQYRRKLR 854

  Fly   818 EK---TSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKEL-PLPIDPSMFPTWPAKSELGARKAQ 878
            |:   .....|.|...:|..||.:|.:|:.||...|.::: |..:.|...|.|....||.::|.:
 Frog   855 EEFVFIPNAALDLFDHMLALDPNKRCTAEQALLCEFLRDVDPSKMTPPDLPLWQDCHELWSKKRR 919

  Fly   879 ASS----------PKPPSGGSQFKQLGRDEPIIVGP-GNKLSSGIITGNKKSHGAGGSSASTGFV 932
            ...          ||.|...|   .||.|:.....| |.::||.:.|....|.|.|  :.|:|..
 Frog   920 RQKQLGMGDDLTVPKVPRKDS---SLGMDDSRNSTPQGMQISSQLKTQGFPSVGVG--NPSSGQQ 979

  Fly   933 LN 934
            ||
 Frog   980 LN 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	120/310 (39%)
		PLN00009	555..854	CDD:177649	120/310 (39%)
cdk13	XP_002940845.2	STKc_CDK12	590..891	CDD:270847	121/312 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920