Protein Alignment CG4042 and DMAC2L

DIOPT Version :10

• Sequence 1: NP_649250.2
• Gene: CG4042 / 40291
• FlyBaseID: FBgn0037018
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: XP_011534954.2
• Gene: DMAC2L / 27109
• HGNCID: 18799
• Length: 244
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 51/220 - (23%)
• Similarity: 96/220 - (43%)
• Gaps: 26/220 - (11%)

  Fly    65 PEDWNSKLKLFSNAEQTSDFIVMMQKPIDLSPRNIRQWWENREERIERHMQQFVPERHKILGAEL 129
            |..||.::..|....|  ....:.:.|.....|....|......:::.       :|.:.:|.:.
Human    38 PAMWNYQMMPFGKISQ--QLCGVKKLPWSCDSRYFWGWLNAVFNKVDY-------DRIRDVGPDR 93

  Fly   130 AAAHFILYRGGAVKFINDTHWRRASKDGEFKLPNKFDPRYKVEALRCDN---MELYYEGLENLRC 191
            ||:.::|..|..|::.....|:   ||.. .||.....:||::|:...:   |.:.::.:|.|..
Human    94 AASEWLLRCGAMVRYHGQERWQ---KDYN-HLPTGPLDKYKIQAIDATDSCIMSIGFDHMEGLEH 154

  Fly   192 LDSLKFLSFHNVKSFDDWCLDRISGGGFPNLE--VLD---LSCTQITSNGLACLYRFPKLKLLIL 251
            ::.::....|.:   :|.||.|:|  ...||:  :|:   :||..||..|:..|.....||.|:|
Human   155 VEKIRLCKCHYI---EDDCLLRLS--QLENLQKTILEMEIISCGNITDKGIIALRHLRNLKYLLL 214

  Fly   252 NDPKETLELELSTVMLEEAMPALKI 276
            :|.....|.|......:.|:|:|::
Human   215 SDLPGVREKENLVQAFKTALPSLEL 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4042	NP_649250.2	leucine-rich repeat	192..221	CDD:275381	6/28 (21%)
		leucine-rich repeat	222..245	CDD:275381	8/27 (30%)
DMAC2L	XP_011534954.2	leucine-rich repeat	155..179	CDD:275381	6/28 (21%)
		leucine-rich repeat	180..208	CDD:275381	8/27 (30%)