Protein Alignment CG13252 and ZAN

DIOPT Version :9

• Sequence 1: NP_649248.3
• Gene: CG13252 / 40289
• FlyBaseID: FBgn0037016
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_003377.2
• Gene: ZAN / 7455
• HGNCID: 12857
• Length: 2812
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 86/411 - (20%)
• Similarity: 129/411 - (31%)
• Gaps: 131/411 - (31%)

  Fly    28 TLDQEPLPD---------LCQSVKCPPDAEMQC----PADSSIRHNLLAVDLIKSNAV------- 72
            :||....||         |..:.|.|..:|..|    ...||.:.|.:|....|:.|:
Human  1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGP 1751

  Fly    73 ------ELPNASEMASAADGVSYNRG-----LISDEDYVQCCL---------NR-----KCVCKT 112
                  .:|..|..||...|....:|     ..|.:.|...|.         ||     :|...:
Human  1752 FSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGS 1816

  Fly   113 CYIPDCPSDADEDVVVVELVPENNQTPGECCGTYECQAEPNCTVVRDTDFHWLKQCRRCKCESGL 177
            .|.| |.|...:....:     ||  |.:|.....|                   ...|:|:.|.
Human  1817 SYSP-CSSPCPDTCSSI-----NN--PRDCPKALPC-------------------AESCECQKGH 1854

  Fly   178 KICHKTCDERAEGVCQSKISGMFYKDGENW-TENCKT--CECE-KGEPKCTMSFC---------- 228
            .:...:|....:..|... :|.::..||.| |||..|  |.|. .....|..|.|
Human  1855 ILSGTSCVPLGQCGCTDP-AGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALD 1918

  Fly   229 GNLNC----------PSEQQVM--------LKDTC----CPVCWPKCAPMP-------HEKQDDG 264
            |.|:|          |.|...:        :.|.|    ..||.|..| :|       |||::.|
Human  1919 GLLHCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA-LPFFKISAKHEKEEGG 1982

  Fly   265 S--------YEDYVDESETPEEDSLPPLLPDPLTTQQSAELVATSTTTSSNGTTSTTVVPLAATV 321
            :        |.|..|...|.::.....:....:|....:::...|..:||  ..|...:.:...|
Human  1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSS--IYSIVNIKIGVQV 2045

  Fly   322 NCNNAFDQPKVVEVVNQTNYY 342
            .    ||...::|:...|.||
Human  2046 K----FDGNHLLEIEIPTTYY 2062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	20/87 (23%)
ZAN	NP_003377.2	MAM	41..203	CDD:306977
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..84
		MAM	211..367	CDD:306977
		MAM	373..535	CDD:306977
		Atrophin-1	<540..1022	CDD:331285
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	545..884
		66 X heptapeptide repeats (approximate) (mucin-like domain)	573..1041
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	904..929
		TIL	1044..1093	CDD:307783
		TILa	1095..1148	CDD:315397
		VWD	1156..1308	CDD:306577
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1302..1323
		C8	1349..1423	CDD:214843
		TIL	1426..1479	CDD:307783
		TILa	1481..1535	CDD:315397
		VWD	1542..1695	CDD:306577	2/7 (29%)
		C8	1742..1808	CDD:312319	12/65 (18%)
		TILa	1869..1924	CDD:315397	16/55 (29%)
		VWD	1931..2084	CDD:306577	29/139 (21%)
		C8	2149..2207	CDD:312319
		TIL	2211..2267	CDD:307783
		TILa	2269..2320	CDD:315397
		VWD	2331..2484	CDD:306577
		C8	2543..>2597	CDD:214843
		TILa	2654..2707	CDD:315397
		EGF	2712..2740	CDD:306513

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900