DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13252 and Vit

DIOPT Version :9

Sequence 1:	NP_649248.3	Gene:	CG13252 / 40289	FlyBaseID:	FBgn0037016	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_083089.1	Gene:	Vit / 74199	MGIID:	1921449	Length:	650	Species:	Mus musculus

Alignment Length:	242	Identity:	44/242 - (18%)
Similarity:	73/242 - (30%)	Gaps:	80/242 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 VVVVELVPENNQTPGECCGTYECQAEPNCTV----VRDTDFHWLKQCRRCKCESGLK-------- 178
            |::|..:..|.:||.:.........:.||.|    :.:.:|       ..||.:|.:
Mouse    18 VLLVTGIHSNKETPKKTKRPKLTVPQINCDVKAGKIINPEF-------MVKCPAGCQDPKYHVYG 75

  Fly   179 ---------IC----HK-TCDERAEGVCQSKISGM-----FYKDG------ENWTENCKTCECEK 218
                     :|    |. ..|.....:...|::|.     .|.:|      ..|.|:....|
Mouse    76 TGVYASYSSVCGAAIHSGVLDNSGGKILVRKVAGQSGYKGSYSNGVQSLSLPRWRESFIVAE--- 137

  Fly   219 GEPKCTMSFCGNLNCPSEQQVMLKDTCCPVCWPKCAPMPHEKQDDGSYEDYVDESETPEEDSLPP 283
            .:|:..:::...|...|.:....|                             ..||.:....|.
Mouse   138 SKPQKGVAYPSTLTYSSSKTAAAK-----------------------------AGETTKAYEKPS 173

  Fly   284 LLPDPLTTQQSAELVATSTTTSSNGTTSTTVVPLAATVNCNNAFDQP 330
            :   |.||.|...|.....|..:..|..:|..|.||:|. |:...||
Mouse   174 I---PGTTIQPVTLTQAQATPVAEVTHRSTSKPFAASVT-NSPRPQP 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13252	NP_649248.3	VWC	197..249	CDD:302663	10/62 (16%)
Vit	NP_083089.1	LCCL	44..133	CDD:281766	16/95 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..226		8/20 (40%)
		vWFA	265..428	CDD:294047
		vWA_collagen	466..626	CDD:238749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900