DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG13252 and Muc5b

DIOPT Version :9

Sequence 1:NP_649248.3 Gene:CG13252 / 40289 FlyBaseID:FBgn0037016 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_083077.2 Gene:Muc5b / 74180 MGIID:1921430 Length:4800 Species:Mus musculus


Alignment Length:307 Identity:63/307 - (20%)
Similarity:97/307 - (31%) Gaps:105/307 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 IFVSSATTLDQEPLPDL--------CQSVKCPP-DAEMQCPADSSIRHNLLAVDLIKSNAVELPN 76
            |.||....:..:.||..        ||:..|.| ...:||             :.:|..:.:.|.
Mouse  4454 ICVSECPCVGPDGLPKFPGEHWISNCQACVCEPGSVSVQC-------------EPVKCESQDKPP 4505

  Fly    77 ASEMAS-------AADGVSYNRGLISDEDYVQCCLNRKCVCK--TC--YIPDCPSDADEDVVVVE 130
            ....|.       :||.              .||....|||.  ||  .:|.|...       .|
Mouse  4506 QCTEAGFVTVTWPSADN--------------PCCPETLCVCNSTTCPKSLPTCEPG-------YE 4549

  Fly   131 LVPENNQTPGECCGTYECQAE--------------------PNCTVVRDTDFHWLKQCRRCKCES 175
            ||..:..:  .||.:|.|:.:                    ..||.:.|.|.....:|:...|.:
Mouse  4550 LVQTHENS--SCCPSYSCRPKLCTYNDTIYGVGTTFPGGPCHTCTCLSDGDQEPKVECKETNCTT 4612

  Fly   176 ----GLK---ICHKTCDERAEGVCQSKISGMFYKDGENW----TENCKT--CECEKGEPKCT--M 225
                |.|   :..:.|.|..:..|.:. .|...:..|.|    .:||..  |..|.|....|  .
Mouse  4613 SCPQGFKYTLVPEQCCGECLQNACLTP-EGHAVQPNETWVNSPVDNCTAYHCMAENGVYVLTPIP 4676

  Fly   226 SFCGNL-NCPSEQQVMLKDTCCPVCWPKCAPMPHEKQDDGSYEDYVD 271
            :.|.:: ||..   .:.|..||..|         ||:|..:.:.:|:
Mouse  4677 TSCPDVSNCTG---TLRKTGCCYSC---------EKEDSSTCQVHVN 4711

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13252NP_649248.3 VWC 197..249 CDD:302663 15/60 (25%)
Muc5bNP_083077.2 VWD 80..227 CDD:214566
C8 263..329 CDD:285899
TIL 333..389 CDD:280072
VWC_out 391..>436 CDD:214565
VWD 418..582 CDD:214566
C8 619..700 CDD:214843
TIL 710..756 CDD:280072
TIL 798..859 CDD:280072
VWD 888..1047 CDD:214566
C8 1087..1157 CDD:285899
Mucin2_WxxW 1345..1432 CDD:290069
Mucin2_WxxW 1574..1663 CDD:290069
NUDE_C <1676..1796 CDD:282704
Mucin2_WxxW 1870..1959 CDD:290069
Mucin2_WxxW 2184..2273 CDD:290069
Mucin2_WxxW 2498..2587 CDD:290069
Mucin2_WxxW 2687..2776 CDD:290069
Herpes_BLLF1 <2920..3410 CDD:282904
Mucin2_WxxW 3066..3155 CDD:290069
Mucin2_WxxW 3380..3469 CDD:290069
PHA03255 3475..>3621 CDD:165513
Mucin2_WxxW 3625..3713 CDD:290069
Mucin2_WxxW 3779..3867 CDD:290069
VWD 4111..4283 CDD:214566
C8 4336..4398 CDD:285899
VWC 4570..4631 CDD:214564 9/60 (15%)
CT 4708..4790 CDD:214482 1/4 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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